Knowledge About the Administration and Regulation of High Alert Medications Among Nurses in Mansoura University Children's Hospital: A Hospital-wide Audit

NCT ID: NCT07243431

Last Updated: 2025-11-21

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 335 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-02-12
• Study Completion Date: 2025-09-12

Brief Summary

This study checks how well nurses at Mansoura University Children's Hospital know about high-alert medications (HAMs). These are drugs that can cause serious harm if given incorrectly. We used a questionnaire to assess their knowledge and identify any gaps. The goal is to improve training and reduce medication errors in the hospital.

Detailed Description

Background:

Medication errors (MEs) are a major cause of patient harm, especially in pediatric settings. High-alert medications (HAMs) are drugs that carry a heightened risk of causing significant patient harm when used in error. Nurses play a critical role in the safe administration of HAMs. This hospital-wide audit aims to evaluate nurses' knowledge regarding the administration and regulation of HAMs at Mansoura University Children's Hospital.

Objectives:

1. To assess the level of knowledge about HAMs among nurses.

2. To identify factors associated with sufficient knowledge of HAMs.

Methods:

A cross-sectional study was conducted using a self-administered questionnaire distributed to all nurses involved in medication administration at Mansoura University Children's Hospital. The questionnaire covered identification of HAMs, storage, administration protocols, and error prevention strategies. Data was collected from [February to October 2025] and analyzed using descriptive statistics and logistic regression.

Setting:

Mansoura University Children's Hospital, Mansoura, Egypt.

Participants:

All registered nurses working in the hospital and involved in medication administration.

Outcome Measures:

• Primary: Level of knowledge about HAMs (scored as sufficient/insufficient).
• Secondary: Factors associated with sufficient knowledge (e.g., years of experience, training).

Conditions

Nurses' Knowledge of High-alert Medications in Pediatric Care

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Eligibility Criteria

Inclusion Criteria

• - Registered nurses working at Mansoura University Children's Hospital.
• Involved in medication administration.
• At least 6 months of experience in the hospital.

Exclusion Criteria

• Non-nursing staff.
• Nurses not involved in direct patient care or medication administration.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Omar Hamdy

OTHER

Sponsor Role: lead

Responsible Party

Omar Hamdy

prof

Responsibility Role: SPONSOR_INVESTIGATOR

Locations

Mansoura University Children's Hospital

Al Mansurah, , Egypt

Countries

Egypt

Other Identifiers

R.25.01.3028

Identifier Type: -

Identifier Source: org_study_id