The Relationship Between Central Sensitization, Pain, and Psychosocial Factors in Individuals With Lipedema

NCT ID: NCT07240285

Last Updated: 2025-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-10-10

Study Completion Date

2025-11-10

Brief Summary

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This cross-sectional study will include women aged 18-75 with clinically diagnosed lipedema and healthy controls. Sociodemographic and clinical data will be collected, and participants will complete the Central Sensitization Inventory (CSI), Visual Analog Scale (VAS), Hospital Anxiety and Depression Scale (HADS), and Pain Catastrophizing Scale (PCS). Pain pressure thresholds (PPT) will be assessed using a digital algometer at the middle deltoid, lateral thigh, and medial knee, with three measurements taken at each site and the average recorded.

Detailed Description

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Conditions

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Lipedema

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Lipedema group

Patients with lipedema

No interventions assigned to this group

Control group

Patients without lipedema

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Clinically diagnosed with lipedema
* Aged between 18 and 75 years
* Provided voluntary informed consent

Exclusion Criteria

* History of systemic diseases such as diabetes, rheumatologic disorders, or malignancy
* Presence of neurological disorders (e.g., polyneuropathy, multiple sclerosis, history of stroke)
* Currently under active psychiatric treatment Pregnancy
* History of lower extremity surgery or major trauma within the past 6 months
* Received injection therapy or physical therapy for the lower extremities within the past 6 -months
* History of infection or active dermatological disease affecting the lower extremities
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Istanbul Physical Medicine Rehabilitation Training and Research Hospital

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Istanbul Physical Medicine Rehabilitation Training and Research Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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Istftreah

Identifier Type: -

Identifier Source: org_study_id

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