South Asians With Type 2 Diabetes at Risk for Depression

NCT ID: NCT07219667

Last Updated: 2025-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-30

Study Completion Date

2028-12-31

Brief Summary

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This study will adapt a community health worker (CHW)-led Type 2 diabetes (T2D) intervention to include mental health and digital components using a trauma informed care approach, and test the feasibility and acceptability of this intervention to support South Asians with T2D at risk for depression.

Detailed Description

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Specific Aim 1: Examine factors associated with distress, poor mental health, and comorbid T2D and depression among South Asians to inform pilot study structure and content.

Specific Aim 2: Adapt CHW-led T2D intervention to include mental health and digital components using a trauma-informed care approach and the ecological validity model.

Specific Aim 3: Evaluate the feasibility and acceptability of a pilot CHW-led intervention to support participants with T2D who are at risk for depression.

Conditions

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Type 2 Diabetes

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Adult South Asian patients in the New York City (NYC) region

In Aim 3, CHWs will provide culturally and linguistically tailored health education to South Asian participants on the management of T2D and depressive symptoms.

Group Type EXPERIMENTAL

CHW-led T2D Intervention

Intervention Type BEHAVIORAL

CHW-led T2D intervention that includes mental health and digital health components.

Interventions

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CHW-led T2D Intervention

CHW-led T2D intervention that includes mental health and digital health components.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Aim 1 (Qualitative Component):

* South Asian ethnicity based on self-report information
* 18 years of age or older
* Residing in NYC
* Willingness and capacity to provide consent

Aim 3: Pilot Intervention:

* South Asian ethnicity based on patient demographic information
* 18 to 75 years of age
* Appointment for routine non-emergent primary care in the past 12 months
* Diagnosis of Type 2 diabetes
* Patient Health Questionnaire-9 (PHQ-9) score of ≥5 (mild to severe depression)
* Residing in NYC
* Willingness and capacity to provide consent

Exclusion Criteria

Aim 1 (Qualitative Component):

• Diagnosed cognitive deficits or limited decision-making capacity

Aim 3: Pilot Intervention:

* Pregnant at the time of screening
* Type 1 diabetes or diabetes secondary to other conditions (e.g., steroid-induced, pancreatic insufficiency)
* Malignancy or life-threatening illness with a life expectancy of \<5 years
* Inability to perform unsupervised physical activity
* Diagnosed cognitive deficits or limited decision-making capacity
* Currently taking anti-depressant medication or receiving counseling services.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

Sponsor Role collaborator

NYU Langone Health

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Naheed Ahmed, PhD

Role: PRINCIPAL_INVESTIGATOR

NYU Langone Health

Locations

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NYU Langone Health

New York, New York, United States

Site Status

Countries

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United States

Central Contacts

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Naheed Ahmed, PhD

Role: CONTACT

646-501-3751

Other Identifiers

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1K01DK140613-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

25-00438

Identifier Type: -

Identifier Source: org_study_id

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