Dermabrasion in Mohs: Split-Scar Trial

NCT ID: NCT07213921

Last Updated: 2025-10-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-23

Study Completion Date

2026-09-30

Brief Summary

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The purpose of this study is to determine the potential influence of intraoperative dermabrasion on scars following Mohs Micrographic Surgery (MMS). Researchers are trying to determine if dermabrasion, a method to gently remove the top layer of your skin, is a good or bad tool to improve scar appearance after healing. The use of dermabrasion technique in this study is considered investigational. 50 participants will be enrolled and on study for up to 6 months.

Detailed Description

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Primary Objective: Scar assessment at 3 months postoperatively by utilizing observer component of Patient and Observer Scar Assessment Scale (POSAS)

Secondary Objectives:

* Patient portion of POSAS
* Overall patient opinion of scar appearance
* Complication rate

Conditions

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Wound Heal

Keywords

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dermabrasion scars

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

This is a single center, randomized, evaluator and participant blind, split wound study.
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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A: Superior Side of the Wound

The participant's wound will be labeled A if it is on the left or superior side of the investigator

Group Type EXPERIMENTAL

Dermabrasion

Intervention Type PROCEDURE

First, both sides of the wound will be sutured together with a subcutaneous (bottom) layer of stitches. Next, a predetermined, concealed randomization number will be obtained which will specify which side, A or B, will be treated with dermabrasion. An electrocautery scratch pad will be used along the wound edge of the intervention side until pin-point bleeding is achieved. This will add no additional time to the standard of care surgery time. The wound will then be closed with an epidermal (top) layer of stitches, as is the standard of care.

B: Inferior Side of the Wound

The participant's wound will be labeled B if it is on the right or inferior side of the investigator

Group Type EXPERIMENTAL

Dermabrasion

Intervention Type PROCEDURE

First, both sides of the wound will be sutured together with a subcutaneous (bottom) layer of stitches. Next, a predetermined, concealed randomization number will be obtained which will specify which side, A or B, will be treated with dermabrasion. An electrocautery scratch pad will be used along the wound edge of the intervention side until pin-point bleeding is achieved. This will add no additional time to the standard of care surgery time. The wound will then be closed with an epidermal (top) layer of stitches, as is the standard of care.

Interventions

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Dermabrasion

First, both sides of the wound will be sutured together with a subcutaneous (bottom) layer of stitches. Next, a predetermined, concealed randomization number will be obtained which will specify which side, A or B, will be treated with dermabrasion. An electrocautery scratch pad will be used along the wound edge of the intervention side until pin-point bleeding is achieved. This will add no additional time to the standard of care surgery time. The wound will then be closed with an epidermal (top) layer of stitches, as is the standard of care.

Intervention Type PROCEDURE

Other Intervention Names

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electrocautery scratch pad

Eligibility Criteria

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Inclusion Criteria

* Able to give informed consent themselves
* Scheduled for cutaneous surgical procedure on the face or neck with predicted linear closure greater than 4 centimeters.
* Willing to return for follow up visit within the evaluation period

Exclusion Criteria

* Patients with impaired decision-making capacity
* Significant vision or hearing impairments
* Pregnant Individuals
* Incarceration
* Wounds with predicted closure length less than 4 cm
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Wisconsin, Madison

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Gloria Xu, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

UW School of Medicine and Public Health

Locations

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UW Health Mohs Surgery Clinic

Madison, Wisconsin, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Dermatology Research

Role: CONTACT

Phone: 608-287-2622

Email: [email protected]

Other Identifiers

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A534300

Identifier Type: OTHER

Identifier Source: secondary_id

Protocol Version 3/21/25

Identifier Type: OTHER

Identifier Source: secondary_id

2025-0592

Identifier Type: -

Identifier Source: org_study_id