Relationship Between Cognition, Workforce Participation and Well-Being in Individuals With Multiple Sclerosis

NCT ID: NCT07211516

Last Updated: 2025-10-08

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 75 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-04-30
• Study Completion Date: 2026-11-30

Brief Summary

Multiple sclerosis (MS) is a chronic neurodegenerative disease and a leading cause of reduced workforce participation due to neurological illness in Western countries. Over the past 30 years, new treatments have reduced symptom burden, allowing patients to stay in the workforce longer. However, fatigue and cognitive impairments remain major barriers to work capacity. This project aims to examine factors important for work ability and well-being in persons with MS and cognitive impairments. The specific research questions are:

1. How do job type and opportunities for workplace adaptations influence work ability and well-being in individuals with MS and cognitive impairments?

2. What are the associations between cognitive function in MS and work ability as well as well-being? The investigators plan to collect data on patients with MS who have undergone a neuropsychological assessment at the neurology clinic in Region Gävleborg over a five year period. Approximately 100 patients are eligible for participation. Data will be collected through surveys and by extracting information from medical records. The surveys include questions related to well-being and work ability. Data from medical records contain data from the neuropsychological assessment, other rehabilitation interventions as well as data related to treatment and progress of MS.

The findings from the study aim to enhance work-oriented rehabilitation and provide a deeper understanding of how to support individuals with MS in maintaining employment and overall well-being

Conditions

Multiple Sclerosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: RETROSPECTIVE

Study Groups

Patients with MS and of working age (18-65) who have been referred to neuropsychological evaluation.

Time of neuropsychological assessment from 5 years before until study start.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

Multiple sclerosis Age between 18-65 Performed a neuropsychological assessment at the Neurology department at Gävle Hospital during the last 5 years (counting from study start) -

Exclusion Criteria

Other diagnosis hindering work participation more than MS

-

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

University of Gavle

OTHER

Sponsor Role: collaborator

Region Gävleborg

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Gävle hospital

Gävle, , Sweden

Countries

Sweden

Central Contacts

Natascha Ekdahl

Role: CONTACT

natascha.ekdahl@regiongavleborg.se

+4626278023

Facility Contacts

Natascha Ekdahl

Role: primary

natascha.ekdahl@regiongavleborg.se

+4626278023

Other Identifiers

MSCogWork2

Identifier Type: -

Identifier Source: org_study_id