Linking Diet, Inflammation, Gut Microbiota, and Sarcopenia: A Cross-Sectional Study

NCT ID: NCT07211321

Last Updated: 2025-10-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

1220 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-04-16

Study Completion Date

2025-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Based on the analysis of dietary characteristics, gut microbiota diversity, and composition, this study investigates the relationships between the dietary inflammatory potential, gut microbiota, and sarcopenia. Furthermore, it explores the mediating role of gut microbiota in the association between the dietary inflammatory index and the risk of sarcopenia. The findings are expected to provide insights into the mechanisms through which dietary inflammation influences the development and progression of sarcopenia, and to offer a basis for dietary and nutritional interventions aimed at preventing or managing this condition.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Sarcopenia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

sarcopenia group and control group

No Intervention: Observational Cohort

Intervention Type OTHER

No Intervention

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

No Intervention: Observational Cohort

No Intervention

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Permanent residents of the community aged 60 years or older.
* Continuous residence duration in the community for more than 5 years.

Exclusion Criteria

* Taking medications known to affect muscle function (e.g., corticosteroids, protein supplements, muscle enhancers).
* Requiring walking assistance or having severe cognitive impairment that would preclude successful completion of assessments including bioelectrical impedance analysis (BIA), gait speed measurement, and handgrip strength testing.
* Presence of a cardiac pacemaker, which contraindicates BIA measurement.
* Diagnosis of one or more chronic diseases that significantly limit dietary intake.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Jianhua Ma

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jianhua Ma

Lecturer

Responsibility Role SPONSOR_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Lanzhou university

Lanzhou, Gansu, China

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

China

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Jianhua Ma Doctor of Medicine

Role: CONTACT

0086 18993157029

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Jie Li Master student

Role: primary

0086 15698480898

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

No. 23JRRA1064

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

IRB23070101

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Skeletal Muscle in PASC and ME/CFS Patients
NCT05225688 ACTIVE_NOT_RECRUITING