Relationship of Radiographic Findings With Pain, Function, Physical Performance and Balance

NCT ID: NCT07186374

Last Updated: 2025-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

72 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-20

Study Completion Date

2025-12-31

Brief Summary

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The objective of this investigation was to examine the correlation between radiographic findings and clinical outcomes, including pain, functional ability, physical performance, and balance parameters, in patients diagnosed with hip osteoarthritis (PwHOA).

Detailed Description

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A total of seventy-two patients with hip osteoarthritis (PwHOA) will be enrolled in the study. Sociodemographic variables will be collected, and assessments will include the Kellgren-Lawrence Classification, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Timed Up and Go Test (TUG), and Four Square Step Test (FSST). The Spearman rank correlation coefficient will be employed to analyze the relationships among pain levels, functional capacity, physical performance, balance, and radiographic findings.

Conditions

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Hip Osteoarthritis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients with Hip Osteoarthritis (PwHOA)

Adults diagnosed with hip osteoarthritis will be included in the study.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* patients with symptomatic and radiographic diagnosis of Grade I-IV hip osteoarthritis according to the Kellgren-Lawrence classification and American College of Rheumatology criteria.

Exclusion Criteria

* patients who did not give consent to participate in the study;
* secondary HOA due to rheumatoid arthritis, tumors, and recent fractures;
* history of intra-articular injections within the last six months.
Minimum Eligible Age

40 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Artvin Coruh University

OTHER

Sponsor Role lead

Responsible Party

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Zeynep Yıldız Kızkın

Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zeynep Yıldız Kızkın, Dr.

Role: PRINCIPAL_INVESTIGATOR

Artvin Coruh University

Locations

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Zeynep Yıldız Kızkın

Artvin, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Zeynep Yıldız Kızkın, Dr.

Role: CONTACT

5346945085 ext. +90

Facility Contacts

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Zeynep Yıldız Kızkın, Lecturer

Role: primary

5346945085 ext. +90

References

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Nelson AE, Hu D, Arbeeva L, Alvarez C, Cleveland RJ, Schwartz TA, Murphy LB, Helmick CG, Callahan LF, Renner JB, Jordan JM, Golightly YM. Point prevalence of Hip Symptoms, Radiographic, And Symptomatic OA at Five Time Points: The Johnston County Osteoarthritis Project, 1991-2018. Osteoarthr Cartil Open. 2022 Jun;4(2):100251. doi: 10.1016/j.ocarto.2022.100251. Epub 2022 Mar 15.

Reference Type BACKGROUND
PMID: 36118130 (View on PubMed)

Turkiewicz A, Kiadaliri AA, Englund M. Cause-specific mortality in osteoarthritis of peripheral joints. Osteoarthritis Cartilage. 2019 Jun;27(6):848-854. doi: 10.1016/j.joca.2019.02.793. Epub 2019 Feb 21.

Reference Type BACKGROUND
PMID: 30797945 (View on PubMed)

Katz JN, Arant KR, Loeser RF. Diagnosis and Treatment of Hip and Knee Osteoarthritis: A Review. JAMA. 2021 Feb 9;325(6):568-578. doi: 10.1001/jama.2020.22171.

Reference Type BACKGROUND
PMID: 33560326 (View on PubMed)

Ritsuno Y, Morita M, Mukaino M, Otsuka K, Kanaji A, Yamada J, Saitoh E, Matsumoto M, Nakamura M, Otaka Y, Fujita N. Determinants of Gait Parameters in Patients With Severe Hip Osteoarthritis. Arch Phys Med Rehabil. 2024 Feb;105(2):343-351. doi: 10.1016/j.apmr.2023.08.021. Epub 2023 Sep 7.

Reference Type BACKGROUND
PMID: 37683907 (View on PubMed)

Ozden F, Nadiye Karaman O, Tugay N, Yalin Kilinc C, Mihriban Kilinc R, Umut Tugay B. The relationship of radiographic findings with pain, function, and quality of life in patients with knee osteoarthritis. J Clin Orthop Trauma. 2020 Jul;11(Suppl 4):S512-S517. doi: 10.1016/j.jcot.2020.04.006. Epub 2020 Apr 9.

Reference Type BACKGROUND
PMID: 32774020 (View on PubMed)

Jacobsen S. Adult hip dysplasia and osteoarthritis. Studies in radiology and clinical epidemiology. Acta Orthop Suppl. 2006 Dec;77(324):1-37.

Reference Type BACKGROUND
PMID: 17380595 (View on PubMed)

Riddle DL, Perera RA. American Academy of Orthopedic Surgeons Appropriate Use Criteria for Hip Preservation Surgery: Variables That Drive Appropriateness for Surgery. Arthritis Care Res (Hoboken). 2020 Mar;72(3):405-411. doi: 10.1002/acr.23828.

Reference Type BACKGROUND
PMID: 30675763 (View on PubMed)

Hattori T, Shimo K, Niwa Y, Tokiwa Y, Matsubara T. Association of Chronic Pain with Radiologic Severity and Central Sensitization in Hip Osteoarthritis Patients. J Pain Res. 2021 Apr 22;14:1153-1160. doi: 10.2147/JPR.S296273. eCollection 2021.

Reference Type BACKGROUND
PMID: 33911897 (View on PubMed)

Rondas GA, Macri EM, Oei EH, Bierma-Zeinstra SM, Rijkels-Otters HB, Runhaar J. Association between hip pain and radiographic hip osteoarthritis in primary care: the CHECK cohort. Br J Gen Pract. 2022 Jul 26;72(723):e722-8. doi: 10.3399/BJGP.2021.0547. Online ahead of print.

Reference Type BACKGROUND
PMID: 36127152 (View on PubMed)

Pereira D, Severo M, Santos RA, Barros H, Branco J, Lucas R, Costa L, Ramos E. Knee and hip radiographic osteoarthritis features: differences on pain, function and quality of life. Clin Rheumatol. 2016 Jun;35(6):1555-64. doi: 10.1007/s10067-015-3087-7. Epub 2015 Oct 7.

Reference Type BACKGROUND
PMID: 26445941 (View on PubMed)

Cubukcu D, Sarsan A, Alkan H. Relationships between Pain, Function and Radiographic Findings in Osteoarthritis of the Knee: A Cross-Sectional Study. Arthritis. 2012;2012:984060. doi: 10.1155/2012/984060. Epub 2012 Nov 19.

Reference Type BACKGROUND
PMID: 23209900 (View on PubMed)

Altman R, Asch E, Bloch D, Bole G, Borenstein D, Brandt K, Christy W, Cooke TD, Greenwald R, Hochberg M, et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 1986 Aug;29(8):1039-49. doi: 10.1002/art.1780290816.

Reference Type BACKGROUND
PMID: 3741515 (View on PubMed)

Iidaka T, Horii C, Muraki S, Oka H, Kawaguchi H, Nakamura K, Akune T, Tanaka S, Yoshimura N. Trends in prevalence of hip osteoarthritis over a 10-year period in Japan: The ROAD study 2005-2015. Osteoarthr Cartil Open. 2022 Jun 22;4(3):100285. doi: 10.1016/j.ocarto.2022.100285. eCollection 2022 Sep.

Reference Type BACKGROUND
PMID: 36474937 (View on PubMed)

Batting M, Barker KL. Reliability and validity of the Four Square Step Test in patients with hip osteoarthritis before and after total hip replacement. Physiotherapy. 2019 Jun;105(2):244-253. doi: 10.1016/j.physio.2018.07.014. Epub 2018 Oct 15.

Reference Type BACKGROUND
PMID: 30630621 (View on PubMed)

Canzone A, Roggio F, Patti A, Giustino V, Mannucci C, Di Mauro D, Musumeci G, Bianco A, Trimarchi F. Classification of Physical Activity Programs Based on the Kellgren & Lawrence Scale for Knee Osteoarthritis: A Systematic Review. Musculoskeletal Care. 2024 Dec;22(4):e70019. doi: 10.1002/msc.70019.

Reference Type BACKGROUND
PMID: 39592397 (View on PubMed)

Thumboo J, Chew LH, Soh CH. Validation of the Western Ontario and Mcmaster University osteoarthritis index in Asians with osteoarthritis in Singapore. Osteoarthritis Cartilage. 2001 Jul;9(5):440-6. doi: 10.1053/joca.2000.0410.

Reference Type BACKGROUND
PMID: 11467892 (View on PubMed)

Alghadir A, Anwer S. Effect of retro and forward walking on quadriceps muscle strength, pain, function, and mobility in patients with knee osteoarthritis: a protocol for a randomized controlled trial. BMC Musculoskelet Disord. 2016 Apr 12;17:161. doi: 10.1186/s12891-016-1021-z.

Reference Type BACKGROUND
PMID: 27072798 (View on PubMed)

Other Identifiers

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Hip Osteoarthritis

Identifier Type: -

Identifier Source: org_study_id

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