Phloroglucinol Effectiveness on Shortening the Duration of Active Phase of Labor

NCT ID: NCT07184099

Last Updated: 2025-09-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

134 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-01

Study Completion Date

2025-06-30

Brief Summary

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This study was planned to fill the gaps regarding the effectiveness of phloroglucinol on the duration of active phase of labor.

Detailed Description

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In today's era, the focus has shifted from a "wait and watch" policy to "active intervention sooner than later" to enhance better labor outcomes. Using an ideal antispasmodic drug would help achieve a rapid and prolonged effect on cervical dilation, with no adverse impact on uterine contractions or causing uterine inertia. If the current study finds phloroglucinol effective in shortening the duration of the active phase of labor, it would help achieve better patient outcomes.

Conditions

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Labor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Phloroglucinol group

Phloroglucinol was administered as intravenous stat infusion with Ringer Lactate infusion.

Group Type EXPERIMENTAL

Phloroglucinol

Intervention Type DRUG

Phloroglucinol was administered as intravenous stat infusion with Ringer Lactate infusion.

Placebo group

The patients were given only Ringer Lactate infusion.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Phloroglucinol

Phloroglucinol was administered as intravenous stat infusion with Ringer Lactate infusion.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Pregnant women aged between 18-35 years
* Period of gestation above 37 weeks.

Exclusion Criteria

* Women with cephalopelvic disproportion
* Double scare uterus
* Fetal distress
* Life threatening bleeding
* Eclampsia
* History of heart disease
* Known allergy to phloroglucinol
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Muhammad Aamir Latif

OTHER

Sponsor Role lead

Responsible Party

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Muhammad Aamir Latif

Research Consultant

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Tahira Riaz, FCPS

Role: PRINCIPAL_INVESTIGATOR

Combined military hospital Attock

Locations

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Combined Military Hospital

Attock, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Other Identifiers

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Dr-Tahira-Attock

Identifier Type: -

Identifier Source: org_study_id

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