Frailty Among Renal Transplant Recipients and Relation to Chronic Allograft Dysfunction

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-15

Study Completion Date

2026-01-15

Brief Summary

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The aim of the study is to assess prevalence of frailty among renal transplant recipients in Alexandria University Hospitals and to study the relation between frailty and chronic allograft dysfunction.

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Detailed Description

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With respect to correlates of frailty, although higher comorbidity burden is also a risk factor for frailty among KT candidates, frailty can also occur in the setting of lower comorbidity burdens. Diabetes and serum albumin concentration are also associated with frailty among prevalent dialysis patients.

In addition, individuals with CKD and ESKD who are frail are also more likely to have cognitive impairment and sarcopenia, or low muscle mass, than their non-frail counterparts

Conditions

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Frailty Renal Transplant

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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renal transplant patients

patients will be subjected to:

1. Assessment of frailty by Clinical Frailty Scale.
2. Assessment of nutritional status using Patient Generated Subjective Global Assessment (PG-SGA).
3. Comorbidity assessment using Charlson comorbidity score.
4. Six minutes walk test.
5. Muscle strength assessment using hand grip strength (HGS) dynamometer.

Group Type EXPERIMENTAL

assessment of frailty

Intervention Type DIAGNOSTIC_TEST

This study is a prospective cross-sectional study to assess the prevalence of frailty among 80 cases of renal transplanted patients.

Specific tests will include:

1. Assessment of frailty by Clinical Frailty Scale.
2. Assessment of nutritional status using Patient Generated Subjective Global Assessment (PG-SGA).
3. Comorbidity assessment using Charlson comorbidity score.
4. Six minutes walk test.
5. Muscle strength assessment using hand grip strength (HGS) dynamometer.

Interventions

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assessment of frailty

This study is a prospective cross-sectional study to assess the prevalence of frailty among 80 cases of renal transplanted patients.

Specific tests will include:

1. Assessment of frailty by Clinical Frailty Scale.
2. Assessment of nutritional status using Patient Generated Subjective Global Assessment (PG-SGA).
3. Comorbidity assessment using Charlson comorbidity score.
4. Six minutes walk test.
5. Muscle strength assessment using hand grip strength (HGS) dynamometer.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Renal transplanted patients with GFR more than 30

Exclusion Criteria

* Mentally or physically unfit patients.
* Amputation of lower limb.
* Active neoplasia, chronic liver disease, previous immunological disease.
* Psychiatric disorders.
* Pregnancy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No