Yoga to Improve Disparities in Cancer Survivorship

NCT ID: NCT07165600

Last Updated: 2025-10-20

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 50 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-09-24
• Study Completion Date: 2026-10-31

Brief Summary

This clinical trial tests the impact of a racially concordant trainer led yoga program on quality of life and symptom burden in Black and/or African American cancer survivors. Black individuals in the United States are more affected by cancer, despite modern advances. Cancer treatments can impact physical and mental health and overall quality of life and Black individuals report worse physical function and quality of life and less access to culturally appropriate support services. Yoga has been shown to have a positive impact on cancer and cancer treatment related symptoms and quality of life, however, a one size fits all approach has not been shown to be effective in diverse populations. A trainer that shares the same racial or ethnic background as the participant (racially concordant) may have a positive impact on communication, trust, and may improve accessibility and participation. Participating in a yoga program led by a racially concordant trainer may improve quality of life and symptom burden in Black and/or African American cancer survivors.

Detailed Description

PRIMARY OBJECTIVE:

I. Determine the feasibility and acceptability of a yoga intervention among Black individuals with cancer.

SECONDARY OBJECTIVES:

I. To estimate the effect of the intervention on health-related quality of life.

II. To estimate the effect of the intervention on symptom burden. III. To determine the safety of the intervention.

OUTLINE:

Participants engage in racially concordant trainer led yoga sessions over 60 minutes once weekly (QW) on weeks 1-4 then participate in self-practice video led yoga sessions over 10-15 minutes on weeks 5-8.

After completion of study intervention, patients are followed up at 3 months.

Conditions

Survivorship; Cancer

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: SUPPORTIVE_CARE
• Blinding Strategy: NONE

Study Groups

Yoga Intervention

Participants receive a 4-week yoga intervention consisting of weekly 60-minute yoga sessions led by a trained facilitator. Participants may also participate remotely. At the end of the program, participants will also receive access to online yoga training videos (created by the study team) to continue self-practice.

Group Type: EXPERIMENTAL

Yoga

Intervention Type: OTHER

Physical activity

Interventions

Yoga

Physical activity

Intervention Type: OTHER

Other Intervention Names

Yoga training; Yoga sessions

Eligibility Criteria

Inclusion Criteria

1. Age >=18 years.

2. Able to understand study procedures and to comply with them for the entire length of the study.

3. Ability of individual or legal guardian/representative to understand a written informed consent document, and the willingness to sign it.

4. Diagnosed with any malignancy and/or received any cancer directed therapy within 5 years of enrollment.

5. Be able to speak, read and write in English.

6. Self-identify as Black or African American race.

7. Reside in California.

Exclusion Criteria

1. Contraindication to any study-related procedure or assessment.

a. Participants complete the PAR-Q at screening to ensure that they are physically well enough to enroll in the study. If they report any conditions that may be contraindications to physical activity, physician clearance will be required prior to enrollment.

2. Planned major surgery during the study period.

3. Any major injuries that limit physical activity.

4. Plans to receive any form of further cancer therapy during the study period (exception: individuals with breast or prostate cancer are allowed to be on hormone therapy on the study).

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of California, San Francisco

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Sorbarikor Piawah, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

University of California, San Francisco

Locations

University of California, San Francisco

San Francisco, California, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Bryan Le

Role: CONTACT

bryankhuong.le@ucsf.edu

(415) 502-6313

Facility Contacts

Bryan Le

Role: primary

bryankhuong.le@ucsf.edu

(415) 502-6313

Role: backup

cancertrials@ucsf.edu

877-827-3222

Other Identifiers

NCI-2025-05225

Identifier Type: REGISTRY

Identifier Source: secondary_id

25802

Identifier Type: -

Identifier Source: org_study_id