Developing a Culturally Relevant Supportive Care Program for Black Patients Dealing With Advanced Cancer

NCT ID: NCT05763797

Last Updated: 2025-08-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-13

Study Completion Date

2029-03-31

Brief Summary

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To determine the feasibility of implementing a culturally adapted mind-body intervention (Meditation-Based Support-Adapted; MBS-A) as a supportive care strategy in Black patients diagnosed with a stage III-IV solid malignancy. To target the specific needs of Black advanced cancer patients, we will first conduct formative research that includes quantitative surveys and in-depth interviews of patients and their primary caregivers. The purpose of this formative research is to determine the intervention format for the MBS-A program (family- vs group-based) that promises the greatest likelihood of success and to solicit input on the original MBS intervention regarding content that needs adaptation. Once the intervention format is determined and content adapted, we will conduct a pilot randomized controlled trial (RCT) to examine the feasibility of the MBS-A intervention vs. a dose-matched attention control (AC) group receiving a psychoeducation intervention.

Detailed Description

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Primary Objectives:

The purpose of this RCT is to thoroughly determine the feasibility of the overall RCT design as well as specific intervention procedures in this underserved population to inform if a large efficacy trial is warranted. Our results will lead to future NIH R01 applications in which efficacy and mechanisms of the interventions will be tested using fully powered samples of Black patients with advanced cancer including multicenter trials. The long-term goal is to establish the effectiveness of the MBS-A intervention and widely disseminate the intervention. Ultimately, the intervention is intended to improve cancer control and reduce the double disparity in this underserved patient population.

We propose the following specific aims:

1. Systematically and culturally adapt a meditation-based support intervention (MBS-A) and finalize the intervention components and delivery format that meet the needs of Black patients with advanced cancer.
2. Identify the feasibility of conducting a supportive-care RCT in Black patients with advanced cancer as determined by recruitment and retention rates, randomization and blinding procedures, and intervention delivery.
3. Identify the feasibility of implementing the MBS-A and AC interventions as determined by session attendance, intervention acceptability, and treatment fidelity.

Conditions

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Cancer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Aim 1 (individual interview)

Participants will be interviewed

Group Type EXPERIMENTAL

Individual Interview

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Meditation Exercise

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Aim 2 (supportive care program)

Participants will be assigned to one of two groups

Group Type EXPERIMENTAL

Individual Interview

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Meditation Exercise

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Aim 3 (supportive care program)

Participants will be assessed regarding their program participation

Group Type EXPERIMENTAL

Individual Interview

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Meditation Exercise

Intervention Type BEHAVIORAL

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Interventions

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Individual Interview

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Intervention Type BEHAVIORAL

Meditation Exercise

Group 1, participant will be in a supportive care program with other Black cancer patients in which you will practice meditation.

Group 2, participate will be in a supportive care program with other Black cancer patients that focuses on coping with cancer.

Participants will be asked to participate weekly sessions for 4 weeks (that is a total of 4 sessions) and each session will last about 60 minutes. Both groups will be delivered via Zoom (a web-based videoconferencing service) and led by a master's-level interventionist.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

For Aim 1, in order to be eligible to participate in this study, a patient must meet all of the following criteria:

* Self-identifies as Black/African American
* Is ≥18 years old
* Was diagnosed with a stage III-IV solid tumor
* Is able to provide informed consent

For Aims 2 and 3, in order to be eligible to participate in this study, a patient must meet all of the following criteria:

* Self-identifies as Black/African American
* Is ≥18 years old
* Was diagnosed with a stage III-IV solid tumor
* Is on active treatment (any line)
* Has an ECOG performance status of ≤2
* Has access to the internet
* Is able to provide informed consent

For Aims 2 and 3, if a family-based intervention is selected as the program format, a patient must meet the additional following criterion:

• Has a family caregiver (e.g., spouse, adult child) with whom they currently reside

Also, if a family-based intervention is selected as the program format, a caregiver must meet all of the following criteria:

* Is ≥18 years old
* Has access to the internet
* Is able to provide informed consent

Exclusion Criteria

For Aims 2 and 3, a patient who meets any of the following criteria will be excluded from participation in this study:

* Is pregnant
* Has cognitive deficits that would impede the completion of self-report instruments as deemed by the clinical team
* Participated in in the Aim 1 of this study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Center for Complementary and Integrative Health (NCCIH)

NIH

Sponsor Role collaborator

M.D. Anderson Cancer Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dalnim Cho, PhD

Role: PRINCIPAL_INVESTIGATOR

M.D. Anderson Cancer Center

Locations

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M D Anderson Cancer Center

Houston, Texas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Dalnim Cho, PhD

Role: CONTACT

(713) 745-8476

Facility Contacts

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Dalnim Cho, PhD

Role: primary

713-745-8476

Related Links

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http://www.mdanderson.org

M D Anderson Cancer Center

Other Identifiers

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NCI-2023-01995

Identifier Type: OTHER

Identifier Source: secondary_id

2022-1015

Identifier Type: -

Identifier Source: org_study_id

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