Comparison of Effects of Eggshell Derived Nano Hydroxyapatite and Hydroxyapatite in Management of Periodontal Intrabony Defects

NCT ID: NCT07160101

Last Updated: 2025-09-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

28 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-03-22

Study Completion Date

2025-03-27

Brief Summary

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The aim of the study is to evaluate osseous regenerative efficacy of eggshell derived nanohydroxyapatite in comparison with hydroxyapatite The test group includes patients with intrabony defects where flap surgery will be performed \& Eggshell derived nano hydroxyapatite (ESnHA) is placed.

Detailed Description

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Experimental : Main treatment group Eggshell derived nano hydroxyapatite is placed into defect site Comparator : In patients allocated to control group, only Hydroxyapatite is placed.

Conditions

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Periodontal Intrabony Defects Bone Regeneration

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Test group Eggshell derived nano hydroxyapatite

In Test group after flap reflection \& degranulation, bone graft i.e Eggshell derived nano hydroxyapatite is placed into defect.

Group Type EXPERIMENTAL

Eggshell derived nano hydroxyapatite

Intervention Type OTHER

Eggshell derived nano hydroxyapatite has high solubility and allows faster integration \& replaces with osseous tissue

Control group

In Control group, after flap reflection \& debridment bone graft i.e Hydroxyapatite is placed into defect.

Group Type ACTIVE_COMPARATOR

Hydroxyapatite

Intervention Type OTHER

Hydroxyapatite has similar chemical composition with crystalline structure of native bone

Interventions

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Eggshell derived nano hydroxyapatite

Eggshell derived nano hydroxyapatite has high solubility and allows faster integration \& replaces with osseous tissue

Intervention Type OTHER

Hydroxyapatite

Hydroxyapatite has similar chemical composition with crystalline structure of native bone

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

Presence of Two-walled or three-walled intrabony defects \& Probing pocket depths (PPD) of \>5mm after initial therapy Systemically healthy male and female patients of age \>18 years

Exclusion Criteria

Medically compromised patients Pregnant women, Heavy smokers, and Patients who underwent radiotherapy or chemotherapy
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dr R Viswa Chandra

OTHER

Sponsor Role lead

Responsible Party

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Dr R Viswa Chandra

PROFFESSOR AND HEAD OF THE DEPARTMENT

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Svs Institute of Dental Sciences

Mahbūbnagar, Telangana, India

Site Status

Countries

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India

Other Identifiers

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SVSIDS/PERIO/1/2022

Identifier Type: -

Identifier Source: org_study_id

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