Multiple Sclerosis, Sarcopenia and Respiration

NCT ID: NCT07152015

Last Updated: 2025-09-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-05

Study Completion Date

2025-09-20

Brief Summary

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The goal of this observational study is to evaluate the relationship between respiratory function and sarcopenia in people with multiple sclerosis.

The main questions it aims to answer are:

Is there a relationship between muscle structure and respiratory muscle strength/pulmonary function in MS patients?

Undergo a single session of respiratory muscle strength measurement (e.g., maximal inspiratory pressure \[MIP\], maximal expiratory pressure \[MEP\]) Perform spirometry to assess pulmonary function

Detailed Description

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Conditions

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Multiple Sclerosis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Sarcopenic MS

No interventions assigned to this group

Nonsarcopenic MS

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Being diagnosed with MS by a neurologist
* Being diagnosed with Sarcopenia
* No history of attacks in the last 3 months
* Able to walk with and without support (EDSS\<6.5)

Exclusion Criteria

* Having concomitant lung and heart disease
* Mini Mental score below 24
* Being in pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uskudar University

OTHER

Sponsor Role lead

Responsible Party

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tuba kolaylı

Lecturer

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Tuba Kolaylı Çerezci, PhD(c)

Role: PRINCIPAL_INVESTIGATOR

Uskudar University

Central Contacts

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Tuba Kolaylı Çerezci, PhD(c)

Role: CONTACT

(216)4002222

References

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Sawaya Y, Shiba T, Ishizaka M, Hirose T, Sato R, Kubo A, Urano T. Sarcopenia is not associated with inspiratory muscle strength but with expiratory muscle strength among older adults requiring long-term care/support. PeerJ. 2022 Feb 17;10:e12958. doi: 10.7717/peerj.12958. eCollection 2022.

Reference Type BACKGROUND
PMID: 35194529 (View on PubMed)

Other Identifiers

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sar123

Identifier Type: -

Identifier Source: org_study_id

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