Respiratory Functions in Parkinson's Disease

NCT ID: NCT07010783

Last Updated: 2025-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-01

Study Completion Date

2025-12-31

Brief Summary

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The aim is to examine respiratory functions, inspiratory muscle strength, respiratory function, physical fitness and aerobic capacity in Parkinson's disease patients. Individuals between the ages of 50-80 who have been diagnosed with Parkinson's disease by a neurologist and healthy individuals with similar demographic characteristics will be included in the study as a control group. In addition, patients will be divided into three groups as above and below 2.5 and healthy controls according to the Modified Hoehn and Yahr Scale. Demographic information of the individuals will be recorded and clinical evaluations will be made. The staging of Parkinson's patients will be done with the Modified Hoehn and Yahr Scale, and the severity of the disease will be done with the Unified Parkinson's Disease Rating Scale. The inspiratory muscle strength of the individuals will be evaluated with the PowerBreath K5, respiratory functions with the Pulmonary Function Test device, and physical fitness and aerobic capacity with the Senior Fitness Test.

Detailed Description

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Conditions

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Parkinson Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Early Stage Patients with Parkinson's Disease

According to the Modified Hoehn and Yahr Scale (MHÖ), patients with a score below 2.5

No interventions assigned to this group

Advanced Stage Patients with Parkinson's Disease

According to the Modified Hoehn and Yahr Scale (MHÖ), patients with 2.5 and above

No interventions assigned to this group

Control Group

Healthy individuals with similar demographic characteristics

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age 50 to 80
* Mini Mental State Examination score of 24 to 30
* Diagnosed with Parkinson's Disease by a neurologist

Exclusion Criteria

* Sözlü iletişim kuramama
* Yürüme yardımcısı kullanıma
* Ciddi görme bozukluğu, ek nörolojik bozuklukları ve/veya konjestif kalp yetmezliği olan yaşlılar
* Egzersiz yapılması tavsiye edilmeyen yaşlı yetişkinler.
Minimum Eligible Age

50 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hacettepe University

OTHER

Sponsor Role collaborator

Atılım University

OTHER

Sponsor Role collaborator

Ankara University

OTHER

Sponsor Role lead

Responsible Party

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Büşra Seçkinoğulları Korkusuz

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Süleyman Korkusuz, PhD

Role: STUDY_CHAIR

Atılım University

Ayla Fil Balkan, Assoc Prof

Role: STUDY_CHAIR

Hacettepe University

Gül Yalçın Çakmaklı, Assoc Prof

Role: STUDY_CHAIR

Hacettepe University

Neslihan Durutürk, Prof.Dr

Role: STUDY_CHAIR

Baskent University

Locations

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Atılım University

Ankara, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Büşra Seçkinoğulları Korkusuz, PhD

Role: CONTACT

+905442436914

Facility Contacts

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Süleyman Korkusuz, PhD

Role: primary

+90 538 867 54 80

References

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Shill H, Stacy M. Respiratory function in Parkinson's disease. Clin Neurosci. 1998;5(2):131-5.

Reference Type RESULT
PMID: 10785839 (View on PubMed)

Morris ME, Iansek R, Matyas TA, Summers JJ. Ability to modulate walking cadence remains intact in Parkinson's disease. J Neurol Neurosurg Psychiatry. 1994 Dec;57(12):1532-4. doi: 10.1136/jnnp.57.12.1532.

Reference Type RESULT
PMID: 7798986 (View on PubMed)

Other Identifiers

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E-59394181-604.01-112206

Identifier Type: -

Identifier Source: org_study_id

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