Evaluating the Implementation and Effectiveness of the Pink and Pearl Campaign on Lung Cancer Screening at Christian Hospital

NCT ID: NCT07146568

Last Updated: 2026-01-16

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 5515 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2026-02-16
• Study Completion Date: 2026-08-31

Brief Summary

Inspired by the ongoing Pink & Pearl Campaign, the breast radiology service of Christian Hospital in north St. Louis County will partner with Siteman Cancer Center to pilot this campaign in its mammography clinics in order to promote awareness, referral, and completion of lung cancer screening (LCS) among eligible women. This campaign leverages established infrastructure such as nurse navigation and referral to screening or primary care for further shared decision-making on cancer screening. The purpose of this study is to evaluate the effectiveness of the Pink & Pearl Campaign in improving LCS uptake among LCS-eligible women undergoing mammography at Christian Hospital. This evaluation is grounded in the Integrated Screening Action Model that depicts individual- and environmental-level influences on the screening behavior process. Using an explanatory sequential mixed methods design, which combines both quantitative and qualitative approaches, our specific aims for this proposal are to: a) assess whether the Pink & Pearl Campaign increases referrals and uptake/completion of LCS among LCS-eligible women undergoing screening mammography; b) determine median time-to-screening after referral to LCS; and c) evaluate individual and health system factors influencing LCS uptake and implementation outcomes of the campaign. These implementation outcomes will help identify whether the campaign was put in place successfully or not. This proposal will inform strategies for integrating cancer screening programs to improve poorly performing programs like LCS.

Conditions

Lung Cancer; Cancer of the Lung

Study Design

• Allocation Method: NON_RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: SCREENING
• Blinding Strategy: NONE

Study Groups

Participants - scheduled for mammography and eligible for LCS

All women coming in for breast cancer screening will be assessed for LCS eligibility using a screening questionnaire administered by mammography technicians. Patients who are determined to be eligible for LCS will be asked by the mammography technician if they will opt into being contacted by the nurse navigator, who will facilitate their referral to primary care to schedule a LCS appointment at Siteman Cancer Center.

Group Type: EXPERIMENTAL

Pink and Pearl Campaign

Intervention Type: OTHER

This campaign leverages established infrastructure such as nurse navigation and referral to screening or primary care for further shared decision-making on cancer screening.

Providers

Providers in the breast radiology service who referred women to LCS. Investigators will gather information on the feasibility, acceptability, and appropriateness of the Pink and Pearl project.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

Pink and Pearl Campaign

This campaign leverages established infrastructure such as nurse navigation and referral to screening or primary care for further shared decision-making on cancer screening.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

Eligibility Criteria - Interventional Study

• Undergoing screening mammography at Christian Hospital
• Between the ages of 50-80 years (inclusive)

Eligibility Criteria - Survey and Interview Sub-Studies

• Part of the interventional study
• Reporting a 20 pack-year equivalent of either current smoking history or have quit in the past 15 years
• Can speak and understand English
• Not diagnosed with a serious health problem that will limit life expectancy (such as previous history of lung cancer, symptoms of lung cancer such as hemoptysis or unexplained weight loss of more than 6.8 kg (15 lb) in the previous year)
• Willing and able to get treatment if lung cancer is found
• Able to understand and willing to sign an IRB-approved written informed consent document

Eligibility Criteria - Providers

• At least 20 years of age
• Involved in the breast radiology service or referred at least one patient to the Pink & Pearl Campaign
• Able to provide verbal consent to participate in the interview

• Minimum Eligible Age: 20 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Washington University School of Medicine

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Beryne Odeny, M.D., MPH, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Washington University School of Medicine

Locations

Barnes-Jewish Christian Hospital

St Louis, Missouri, United States

Countries

United States

Central Contacts

Beryne Odeny, M.D., MPH, Ph.D.

Role: CONTACT

beryne@wustl.edu

314-362-1183

Michelle V Lee, M.D.

Role: CONTACT

lee.michelle@wustl.edu

314-454-7405

Facility Contacts

Beryne Odeny, M.D. MPH, Ph.D.

Role: primary

beryne@wustl.edu

314-362-1183

Michelle V Lee, M.D.

Role: backup

lee.michelle@wustl.edu

314-454-7405

Related Links

http://www.siteman.wustl.edu

Alvin J. Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine

Other Identifiers

202508075

Identifier Type: -

Identifier Source: org_study_id