Microplastic Analysis in Pediatric Inflammatory Bowel Disease
NCT ID: NCT07141238
Last Updated: 2025-09-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
40 participants
OBSERVATIONAL
2025-06-15
2026-06-30
Brief Summary
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Are microplastics detectable in different biological samples from children? Are there differences in microplastic burden between children with and without IBD?
Researchers will collect biological samples including: intestinal tissue (from routine endoscopy), stool, urine, blood.
Raman spectroscopy will be used to detect and characterize microplastics in each sample type. Participants will not receive any medication or intervention as part of this study. All samples will be collected during standard clinical procedures.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
CROSS_SECTIONAL
Study Groups
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Pediatric IBD group
Children diagnosed with inflammatory bowel disease (Crohn's disease or ulcerative colitis) undergoing clinically indicated endoscopy. Biological samples, including intestinal biopsies, stool, urine, and blood, will be collected and analyzed for microplastic content using Raman spectroscopy.
Environmental microplastic exposure
Exposure to environmental microplastics measured by their presence in intestinal tissue, blood, urine, and stool using Raman spectroscopy. This study does not assign any exposure or treatment; it investigates the existing presence of microplastics as an environmental factor of interest.
Control group
Children without a diagnosis of IBD undergoing endoscopy for non-inflammatory indications (e.g., polyps, anemia). Biological samples, including intestinal biopsies, stool, urine, and blood, will be collected and analyzed for microplastic content using Raman spectroscopy.
Environmental microplastic exposure
Exposure to environmental microplastics measured by their presence in intestinal tissue, blood, urine, and stool using Raman spectroscopy. This study does not assign any exposure or treatment; it investigates the existing presence of microplastics as an environmental factor of interest.
Interventions
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Environmental microplastic exposure
Exposure to environmental microplastics measured by their presence in intestinal tissue, blood, urine, and stool using Raman spectroscopy. This study does not assign any exposure or treatment; it investigates the existing presence of microplastics as an environmental factor of interest.
Eligibility Criteria
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Inclusion Criteria
* Undergoing clinically indicated gastrointestinal endoscopy
* For IBD group: confirmed diagnosis of Crohn's disease or ulcerative colitis
* For control group: no current or past diagnosis of IBD
Exclusion Criteria
* Lack of informed consent from legal guardian
* Lack of written assent from the participant if age ≥13 years
18 Years
ALL
No
Sponsors
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Medical University of Gdansk
OTHER
Responsible Party
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Locations
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Medical University of Gdańsk, Department of Pediatrics, Gastroenterology, Allergolgy and Nutrition
Gdansk, , Poland
Countries
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Central Contacts
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Facility Contacts
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Michał Brzeziński, Professor
Role: backup
Other Identifiers
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MAP-IBD-2025
Identifier Type: -
Identifier Source: org_study_id
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