"Short-term Outcome in STEMI Patients Undergoing Primary PCI: A Comparative Study Between Rural and Urban Communities at Assiut University."

NCT ID: NCT07136831

Last Updated: 2025-08-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

162 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-15

Study Completion Date

2026-12-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

this study aims to assess the short-term (3-month) clinical and echocardiographic outcomes of primary PCI among STEMI patients from rural versus urban areas in Upper Egypt. A special focus will be placed on identifying predictors of MACE. The findings may offer valuable insight into optimizing STEMI care pathways and support the development of regional STEMI networks across Egypt.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

ST-segment elevation myocardial infarction (STEMI) is a life-threatening condition that requires urgent reperfusion therapy, with primary percutaneous coronary intervention (PCI) being the gold standard of care. While PCI significantly reduces complications and improves survival, access to this intervention remains unequal, particularly between rural and urban populations

According to the latest census definitions, a rural area is characterized by:A population of fewer than 5,000,A population density of less than 400 persons per square kilometer,And more than 25% of the male working population engaged in agriculture.

Rural patients often experience delayed diagnosis, limited access to PCI-capable centers, and prolonged ischemic times. These factors contribute to poorer clinical outcomes, including higher rates of reinfarction, heart failure, and mortality. In contrast, urban residents typically have faster access to specialized cardiac care and more efficient treatment pathways.

In Upper Egypt, this urban-rural gap is particularly pronounced, with rural patients facing substantial logistical and systemic challenges in receiving timely PCI. Although efforts have been made to expand PCI access nationwide, there remains a lack of localized data comparing short-term outcomes-particularly major adverse cardiovascular events (MACE)-between rural and urban STEMI patients.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

MACE In STEMI

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Primary Percutaneous Coronary Intervention (PPCI)

A catheter-based invasive procedure used to open blocked coronary arteries in patients presenting with ST-elevation myocardial infarction (STEMI).

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 1\. Adults aged ≥18 years. 2. Confirmed diagnosis of ST-segment elevation myocardial infarction (STEMI) based on ECG and cardiac biomarkers.

3\. Underwent primary percutaneous coronary intervention (PCI) within the study period.

4\. Known and verified residential address classified as rural or urban based on official definitions (e.g., UK or WHO classification).

5\. Informed consent obtained

Exclusion Criteria

1. Non-STEMI or unstable angina cases.
2. Patients who received fibrinolytic therapy instead of PCI.
3. Transfer from another facility after more than 12 hours of symptom onset.
4. Patients with previous revascularization (e.g., CABG or PCI within the last 6 months).
5. Incomplete clinical data or unknown residential location.

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Assiut University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Fatma Ali Khallaf

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Fatma ali khallaf Dr fatma ali

Role: CONTACT

+201000465132

Hatem Abdelrahman, Professor

Role: CONTACT

+20 10 05212162

Related Links

Access external resources that provide additional context or updates about the study.

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

STEMI-PPCI-RURALURBAN-ASU25

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.