Usability of the MeTime MS App

NCT ID: NCT07123272

Last Updated: 2025-11-20

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-17

Study Completion Date

2025-05-16

Brief Summary

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The Me Time MS Application was designed to enable self-administration of acupressure. Two forms of acupressure - either "relaxing" or "stimulating" protocols - are administered through the Me Time MS app.

The goal of this study is to assess the usability of the Me Time MS app in a sample of 10 adults with multiple sclerosis (MS).

Detailed Description

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Conditions

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Multiple Sclerosis Pain Fatigue Symptom

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Relaxing Self-Acupressure

Self-guided use of a smartphone app that informs users how to administer relaxing acupressure each day for 6 weeks.

Group Type EXPERIMENTAL

Self-guided smartphone application for relaxing acupressure

Intervention Type BEHAVIORAL

Relaxing Acupressure entails applying pressure with either a finger, pencil, or similar object to acupressure points. For the relaxing protocol, there is a total of 9 acupoints (1 unilateral and 4 bilateral). Each point will be stimulated for 3 minutes, yielding a total treatment time of 27 minutes each day. The acupoints are:

1. Yin Tang (Unilaterally): Located on the forehead, between the eyebrows.
2. Anmian (Right and Left/bilaterally): Located on the posterior aspect of the neck, in a slight depression along the bone directly behind the ear.
3. Heart 7 (HT7) (Right and Left/bilaterally): Located on the palmer surface of the hands on the wrist crease; in line with the pinky.
4. Spleen 6 (SP6) (Right and Left/bilaterally): Located on the inside of the lower leg, approximately 4 fingers width above the bone of the ankle.
5. Liver 3 (LIV3) (Right and Left/bilaterally): This point is located on the foot, near the big and second toes.

Stimulating Self-Acupressure

Self-guided use of a smartphone app that informs users how to administer relaxing acupressure each day for 6 weeks.

Group Type EXPERIMENTAL

Self-guided smartphone application for stimulating acupressure

Intervention Type BEHAVIORAL

There is a total of 10 acupoints (2 unilateral and 4 bilateral). Each point is stimulated for 3 minutes, yielding a total treatment time of 30 minutes each day. The acupoints are:

1. Du 20 (Unilaterally): Located at the top of the head.
2. Large Intestine 4 (LI4) (Right and Left/bilaterally): Located on the back of the hand, between your thumb and index finger.
3. Conception Vessel 6 (CV6) (Unilaterally): Located two finger widths below the navel on the centerline.
4. Stomach 36 (ST36) (Right and Left/bilaterally): Located on the lower leg below the knee on the outside of the leg.
5. Spleen 6 (SP6) (Right and Left/bilaterally): Located on the inside of the lower leg, approximately 4 fingers width above the bone of the ankle.
6. Kidney 3 (K3) (Right and Left/bilaterally): Located on the inside of the ankle.

Interventions

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Self-guided smartphone application for relaxing acupressure

Relaxing Acupressure entails applying pressure with either a finger, pencil, or similar object to acupressure points. For the relaxing protocol, there is a total of 9 acupoints (1 unilateral and 4 bilateral). Each point will be stimulated for 3 minutes, yielding a total treatment time of 27 minutes each day. The acupoints are:

1. Yin Tang (Unilaterally): Located on the forehead, between the eyebrows.
2. Anmian (Right and Left/bilaterally): Located on the posterior aspect of the neck, in a slight depression along the bone directly behind the ear.
3. Heart 7 (HT7) (Right and Left/bilaterally): Located on the palmer surface of the hands on the wrist crease; in line with the pinky.
4. Spleen 6 (SP6) (Right and Left/bilaterally): Located on the inside of the lower leg, approximately 4 fingers width above the bone of the ankle.
5. Liver 3 (LIV3) (Right and Left/bilaterally): This point is located on the foot, near the big and second toes.

Intervention Type BEHAVIORAL

Self-guided smartphone application for stimulating acupressure

There is a total of 10 acupoints (2 unilateral and 4 bilateral). Each point is stimulated for 3 minutes, yielding a total treatment time of 30 minutes each day. The acupoints are:

1. Du 20 (Unilaterally): Located at the top of the head.
2. Large Intestine 4 (LI4) (Right and Left/bilaterally): Located on the back of the hand, between your thumb and index finger.
3. Conception Vessel 6 (CV6) (Unilaterally): Located two finger widths below the navel on the centerline.
4. Stomach 36 (ST36) (Right and Left/bilaterally): Located on the lower leg below the knee on the outside of the leg.
5. Spleen 6 (SP6) (Right and Left/bilaterally): Located on the inside of the lower leg, approximately 4 fingers width above the bone of the ankle.
6. Kidney 3 (K3) (Right and Left/bilaterally): Located on the inside of the ankle.

Intervention Type BEHAVIORAL

Other Intervention Names

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Me Time MS Me Time MS

Eligibility Criteria

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Inclusion Criteria

* MS diagnosis (all MS subtypes included)
* Age 18 years or older
* Average Fatigue Severity Scale (FSS) score ≥ 4 at screening coupled with the opinion of the volunteer that the fatigue has interfered with their daily activities for ≥ 3 months
* Presence of chronic pain defined as moderate to severe pain for ≥ 3-month duration that is ≥ 4 on average using a 0-10 numerical rating scale
* Home access to internet via Wi-Fi or cellular data
* Active email account

Exclusion Criteria

* Not fluent in English
* Pregnancy or breast feeding, or anticipate pregnancy in next 6 months
* Inability to use smartphone/tablet and/or MeTime MS mobile app
* Anything at the discretion of the PI or study team that would preclude participation in the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Center for Complementary and Integrative Health (NCCIH)

NIH

Sponsor Role collaborator

University of Michigan

OTHER

Sponsor Role lead

Responsible Party

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Anna Kratz

Principal Investogator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Anna Kratz, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Michigan

Locations

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University of Michigan

Ann Arbor, Michigan, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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K24AT012644

Identifier Type: NIH

Identifier Source: secondary_id

View Link

HUM00268311

Identifier Type: -

Identifier Source: org_study_id

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