European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis

NCT ID: NCT07108803

Last Updated: 2025-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

2500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-01

Study Completion Date

2025-08-31

Brief Summary

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The European Research Group on Outcomes of Surgical Treatment of Infective Endocarditis (ERGOSTE) is a nascent large surgical registry that would encompass most relevant aspects of IE in Europe in the contemporary era.

Detailed Description

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ERGOSTE, Purposes:

* To create a European multicenter retrospective database including a large number of patients undergoing surgical treatment for infective endocarditis (IE).
* To perform epidemiologic analyses of IE-patients and involved pathogens.
* To find independent predictors of early post-operative death.
* To test ALL the scoring systems specifically developed to predict early death after surgery for infective endocarditis.
* To devise a specific risk score for early postoperative death.
* To explore early and late outcomes of these very difficult patients in order to establish optimal indications, techniques and timing of surgery.
* To carry out a number of sub-analyses concerning the demographic parameters and variable clinical presentation of patients, type and severity of cardiac structural involvement, adopted valve prostheses and surgical techniques, and different involved microbiologic agents.
* To lay experiential foundations of a prospective database on the topic.

Conditions

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Infective Endocarditis (IE)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing cardiac surgery due to infective endocarditis

Exclusion Criteria

* Patients under 18 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI)

UNKNOWN

Sponsor Role lead

Responsible Party

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Giuseppe Gatti

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cardiac Surgery Unit - ASUGI

Trieste, TRIESTE, Italy

Site Status

Countries

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Italy

Other Identifiers

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386_2024

Identifier Type: -

Identifier Source: org_study_id

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