Anatomopathological Analysis of the Infundibulopelvic Ligament in Patients With Ovarian Cancer

NCT ID: NCT07100288

Last Updated: 2025-08-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-07-20

Study Completion Date

2030-12-30

Brief Summary

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Involvement of the infundibulopelvic ligament in ovarian cancer may be associated with decreased survival and related to paraaortic lymph node metastasis

Detailed Description

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Conditions

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Ovarian Cancer Ovarian Cancer (OvCa) Ovarian Adenocarcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ovarian cancer patients

resection of infundibulopelvic ligament

Intervention Type OTHER

Therefore, this study also aims to perform bilateral infundibulopelvic ligament resection (at least 8 cm in length) during surgery for ovarian cancer patients

Interventions

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resection of infundibulopelvic ligament

Therefore, this study also aims to perform bilateral infundibulopelvic ligament resection (at least 8 cm in length) during surgery for ovarian cancer patients

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ◦ Patients with epithelial ovarian cancer, including high- and low-grade serous, high- and low-grade endometrioid, mucinous (expansile and infiltrative types), and carcinosarcoma.

* FIGO 2014 stage IA-IVB.
* Patients undergoing primary surgery or interval surgery after 3-4 or 6 cycles of chemtherapy
* Patients with no residual disease after surgery.
* Patients with ECOG performance status 0-1.

Exclusion Criteria

* ◦ Patients without epithelial ovarian cancer.

* Patients with ECOG 2-4.
* Patients who do not consent to participate in the study.
* Patients who did not undergo complete staging surgery (including hysterectomy, bilateral salpingo-oophorectomy, pelvic and para-aortic lymphadenectomy, and omentectomy) or with residual disease after cytoreductive surgery.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Complejo Hospitalario Universitario Insular Materno Infantil

OTHER

Sponsor Role lead

Responsible Party

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Beatriz Fatima Navarro Santana

GYNECOLOGIST ONCOLOGIST

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Complejo Universitario Insular Materno Infantil de Las Palmas

Las Palmas de Gran Canaria, , Spain

Site Status RECRUITING

Countries

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Spain

Central Contacts

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beatriz NAVARRO SANTANA, pHD

Role: CONTACT

+34620151146

Facility Contacts

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Alicia Martin Martinez, phd

Role: primary

+34649088104

Role: backup

References

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Tozzi R, Kohler C, Ferrara A, Schneider A. Laparoscopic treatment of early ovarian cancer: surgical and survival outcomes. Gynecol Oncol. 2004 Apr;93(1):199-203. doi: 10.1016/j.ygyno.2004.01.004.

Reference Type BACKGROUND
PMID: 15047236 (View on PubMed)

Kleppe M, Kraima AC, Kruitwagen RF, Van Gorp T, Smit NN, van Munsteren JC, DeRuiter MC. Understanding Lymphatic Drainage Pathways of the Ovaries to Predict Sites for Sentinel Nodes in Ovarian Cancer. Int J Gynecol Cancer. 2015 Oct;25(8):1405-14. doi: 10.1097/IGC.0000000000000514.

Reference Type BACKGROUND
PMID: 26397066 (View on PubMed)

Fennimore IA, Simon NL, Bills G, Dryfhout VL, Schniederjan AM. Extension of ovarian tissue into the infundibulopelvic ligament beyond visual margins. Gynecol Oncol. 2009 Jul;114(1):61-3. doi: 10.1016/j.ygyno.2009.03.006. Epub 2009 Apr 9.

Reference Type BACKGROUND
PMID: 19361838 (View on PubMed)

Study Documents

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Document Type: preprint

View Document

Other Identifiers

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2024-430-1

Identifier Type: -

Identifier Source: org_study_id

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