Frequency and Severity of Respiratory Acidosis During One-lung Ventilation, a Retrospective Pilot Study to Compare Clinician Settings and Those Proposed by the VentilO Application

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-08-01

Study Completion Date

2026-06-30

Brief Summary

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One-lung ventilation is a mechanical ventilation method frequently used during several thoracic surgeries. One-lung ventilation requires the use of protective ventilation to limit ventilator-induced injury and reduce postoperative respiratory complications. Protective ventilation during one-lung ventilation is specific since tidal volumes are applied by definition to one lung, and it is recommended to use lower tidal volumes, down to 4 ml/kg of ideal body weight. This approach requires individualized ventilation parameters, which differs from the conventional or two-lung ventilation, and there are no clear recommendations regarding respiratory rate adjustment to ensure adequate gas exchange.

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Detailed Description

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The aim of the study is to:

1. Evaluate whether the initial ventilation settings (tidal volume and respiratory rate) during one-lung ventilation are appropriate to prevent respiratory acidosis.
2. Compare the ventilation settings (tidal volume and respiratory rate) made by clinicians with those proposed by an smartphone application ''VentilO''.

Conditions

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Thoracic Surgery Mechanical Ventilation Hypercapnia Acidosis One Lung Ventillation (OLV) Smartphone Application

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Thoracic surgery

Patient managed with one lung ventilation

one lung ventilation

Intervention Type OTHER

Arterial blood gases during one lung ventilation

Interventions

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one lung ventilation

Arterial blood gases during one lung ventilation

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults (≥ 18 years old)
* Patients intubated and undergoing one-lung ventilation during thoracic surgery
* Volume-controlled ventilation mode used intraoperatively