Exploratory Functional Assessment After Lower Limb Amputation: Locomotion, Balance, Energy Performance and Strategies for Adapting to Orthopaedic Devices

NCT ID: NCT07094074

Last Updated: 2025-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-30

Study Completion Date

2031-01-31

Brief Summary

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The general aim of this exploratory study is therefore to investigate and quantify the functional capacities of patients with lower limb amputations (transtibial and transfemoral), with no change in their management, and to describe any changes in these capacities. The volunteers included in this study will be testing new equipment, all of which will be CE-marked, and will therefore meet all the safety and performance conditions required for use by these patients (equipment that is likely to be prescribed as standard). These devices could benefit from current technological advances that could improve these patients' functional abilities. They will be chosen and adapted according to the volunteer's activity and current equipment.

This is a local project of the CHU Dijon Bourgogne which will take place on the Technological Investigation Platform located at the Centre de Rééducation et de Réadaptation of the CHU Dijon Bourgogne.

A maximum of 100 patients will take part in the study, divided into two sub-groups of between 5 and 50 patients, depending on the type of brace worn and the level of amputation.

After the inclusion visit, each volunteer will undergo 2 assessment visits (the order of assessment of the devices will depend on randomisation) separated by 3 to 6 weeks. Follow-up is for a maximum of 14 weeks.

Detailed Description

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Conditions

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Lower Limb Amputation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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No change of equipment at the inclusion visit

Group Type EXPERIMENTAL

Walk tests

Intervention Type OTHER

* 200 m walk test
* 2-minute walk test
* 6-minute walk test

Functional testing

Intervention Type OTHER

Timed Up and Go test (TUG), Berg Balance Test (BBT), Choice Stepping Reaction Time (CSRT), Functional Reach Test (FRT)

Balance analysis

Intervention Type OTHER

Balance analysis

Quantified analysis of walking

Intervention Type OTHER

On flat ground, even on slopes and stairs

Questionnaires

Intervention Type OTHER

Houghton, Prosthetic Profile of the Amputees-Locomotion Capabilities Index (PPA-LCI), Activities-specific Balance Confidence scale (ABC), quality of life assessed by the SF-12

Change of equipment at the end of the inclusion visit

Group Type EXPERIMENTAL

Walk tests

Intervention Type OTHER

* 200 m walk test
* 2-minute walk test
* 6-minute walk test

Functional testing

Intervention Type OTHER

Timed Up and Go test (TUG), Berg Balance Test (BBT), Choice Stepping Reaction Time (CSRT), Functional Reach Test (FRT)

Balance analysis

Intervention Type OTHER

Balance analysis

Quantified analysis of walking

Intervention Type OTHER

On flat ground, even on slopes and stairs

Questionnaires

Intervention Type OTHER

Houghton, Prosthetic Profile of the Amputees-Locomotion Capabilities Index (PPA-LCI), Activities-specific Balance Confidence scale (ABC), quality of life assessed by the SF-12

Interventions

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Walk tests

* 200 m walk test
* 2-minute walk test
* 6-minute walk test

Intervention Type OTHER

Functional testing

Timed Up and Go test (TUG), Berg Balance Test (BBT), Choice Stepping Reaction Time (CSRT), Functional Reach Test (FRT)

Intervention Type OTHER

Balance analysis

Balance analysis

Intervention Type OTHER

Quantified analysis of walking

On flat ground, even on slopes and stairs

Intervention Type OTHER

Questionnaires

Houghton, Prosthetic Profile of the Amputees-Locomotion Capabilities Index (PPA-LCI), Activities-specific Balance Confidence scale (ABC), quality of life assessed by the SF-12

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Person who has given oral consent
* Patient able to understand simple commands and packaging instructions
* Male or female patient over 18 years of age
* Patient with a lower limb amputation, at tibial or femoral level

Exclusion Criteria

* Person not affiliated to or not benefiting from a social security scheme
* Person subject to a legal protection measure (curatorship, guardianship)
* Person subject to a judicial protection measure
* Pregnant women, women in labour or breastfeeding mothers
* Adults who are incapable or unable to give their consent
* Subjects with disarticulated hips
* Subjects with serious associated pathologies having an impact on walking (other than amputation)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire Dijon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Paul ORNETTI

Role: CONTACT

03 80 29 37 45

Other Identifiers

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ORNETTI 2025

Identifier Type: -

Identifier Source: org_study_id

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