Micellar Water and the Skin Barrier: Comparing Rinsing vs. Non-Rinsing Application

NCT ID: NCT07079371

Last Updated: 2025-07-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-06-18

Study Completion Date

2026-01-01

Brief Summary

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The goal of this clinical trial is to assess how micellar water affects the skin barrier in healthy adult volunteers. The main questions it aims to answer are:

* Does leaving micellar water on the skin affect skin barrier function differently than rinsing it off?
* Are there measurable differences in transepidermal water loss (TEWL), skin hydration, and erythema between the two application methods?

Researchers will compare the effects of micellar water left on the skin versus rinsed off after application.

Participants will:

* Be randomly assigned to one of two groups
* Apply micellar water to their forehead once daily for 21 days
* Either leave the micellar water on or rinse it off, depending on their group
* Undergo non-invasive measurements of TEWL, skin hydration, and erythema before and after the intervention

Detailed Description

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Conditions

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Effects of Micellar Water Application on Skin Barrier Integrity, Hydration, and Erythema in Healthy Skin

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Micellar Water Application Without Rinsing

Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing. Skin barrier function is assessed before and after 21 days of application.

Group Type EXPERIMENTAL

Micellar Water Application (No Rinse)

Intervention Type PROCEDURE

Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing for 21 days.

Micellar Water Application With Rinsing

Participants apply micellar water to the forehead once daily and rinse it off after application. Skin barrier function is assessed before and after 21 days of application.

Group Type EXPERIMENTAL

Micellar Water Application (With Rinse)

Intervention Type PROCEDURE

Participants apply micellar water to the forehead once daily and rinse it off after application for 21 days.

Interventions

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Micellar Water Application (No Rinse)

Participants apply micellar water to the forehead once daily and leave it on the skin without rinsing for 21 days.

Intervention Type PROCEDURE

Micellar Water Application (With Rinse)

Participants apply micellar water to the forehead once daily and rinse it off after application for 21 days.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Healthy adult volunteers aged 18 years and older. Willingness and ability to comply with study procedures. Signed informed consent indicating understanding of study participation, rights, and potential risks and benefits. No current skin diseases or conditions at the test site. Ability to attend all study visits and follow instructions
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Split, School of Medicine

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Univerity of Split School of Medicine

Split, , Croatia

Site Status

Countries

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Croatia

Other Identifiers

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2181-198-03-04-25-0065

Identifier Type: -

Identifier Source: org_study_id

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