AI-Based Prediction of Stage and Survival in Non-Small Cell Lung Cancer: A Retrospective Study

NCT ID: NCT07068139

Last Updated: 2025-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2025-09-01

Brief Summary

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This study aims to evaluate the role of artificial intelligence (AI) in predicting disease stage and survival in patients diagnosed with non-small cell lung cancer (NSCLC). Using a retrospective design, the research will analyze radiologic imaging data (PET-CT and chest CT) and corresponding histopathological results of patients who underwent lung cancer surgery at Ondokuz Mayis University Hospital.

The goal is to develop and validate a deep learning-based AI model that can automatically assess preoperative radiologic features and estimate postoperative tumor stage and survival outcomes. By integrating radiologic data with confirmed pathological diagnoses, the AI system is expected to provide clinical decision support that can improve diagnostic speed, reduce human error, and help clinicians predict prognosis more accurately.

This study does not involve any experimental treatment or prospective follow-up of patients. All data will be collected from existing medical records. The findings may contribute to the digital transformation of healthcare and promote the use of AI tools in thoracic oncology.

Detailed Description

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Conditions

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Non-Small Cell Lung Cancer Artificial Intelligence (AI) in Diagnosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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NSCLC Surgery Cohort

This cohort includes patients who were diagnosed with non-small cell lung cancer (NSCLC) and underwent surgical treatment at Ondokuz Mayis University Hospital. Preoperative PET-CT and chest CT images and corresponding postoperative histopathological data were retrospectively collected and analyzed to develop an artificial intelligence model for predicting tumor stage and survival.

AI-Based Predictive Modeling

Intervention Type OTHER

This is not a therapeutic or diagnostic intervention. The study uses a retrospective dataset of radiologic and pathological records to train and validate a deep learning model designed to predict tumor stage and survival in patients with non-small cell lung cancer (NSCLC). No experimental procedure is applied to participants.

Interventions

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AI-Based Predictive Modeling

This is not a therapeutic or diagnostic intervention. The study uses a retrospective dataset of radiologic and pathological records to train and validate a deep learning model designed to predict tumor stage and survival in patients with non-small cell lung cancer (NSCLC). No experimental procedure is applied to participants.

Intervention Type OTHER

Other Intervention Names

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Deep Learning Algorithm, Retrospective Imaging Analysis

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Diagnosed with non-small cell lung cancer (NSCLC)
* Underwent surgical treatment for NSCLC at Ondokuz Mayis University Hospital
* Available preoperative PET-CT and chest CT imaging
* Available postoperative histopathological diagnosis and staging
* Signed informed consent form for data use in research

Exclusion Criteria

* Age \< 18 years
* No available PET-CT or chest CT imaging in hospital records
* No available histopathological diagnosis in hospital records
* Diagnosed with a type of lung cancer other than NSCLC
* Patients who did not undergo surgery
* Patients who did not provide informed consent for retrospective data use
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hilkat Fatih Elverdi

OTHER

Sponsor Role lead

Responsible Party

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Hilkat Fatih Elverdi

Thoracic Surgery Resident

Responsibility Role SPONSOR_INVESTIGATOR

Other Identifiers

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B.30.2.ODM.0.20.08/194-318

Identifier Type: -

Identifier Source: org_study_id

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