Non-Helium Magnetoencephalography in Autism Spectrum Disorder

NCT ID: NCT07064967

Last Updated: 2025-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-05

Study Completion Date

2027-12-31

Brief Summary

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The goal of this observational study is to learn how brain activity in children with autism spectrum disorder (ASD) differs from typical developing children using magnetoencephalography (MEG).

The main questions this study aims to answer are:

Do children with ASD show different patterns of neural oscillation compared to typically developing children? Can MEG identify specific brain features that help ASD diagnosis?

Participants will undergo MEG scan in both resting and tasking state, and their brain activity will be analyzed for characteristic neural oscillations and connectivity patterns.

This study may help develop better tools for early ASD diagnosis.

Detailed Description

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Conditions

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Autism Spectrum Disorder (ASD)

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ASD

Participants in the ASD group consisted of children diagnosed with Autism Spectrum Disorder according to DSM-5 criteria.

Magnetoencephalography

Intervention Type DIAGNOSTIC_TEST

Participants will undergo magnetoencephalography scan in both resting and tasking state.

Control

Participants in the Control group consisted of typically developing children.

Magnetoencephalography

Intervention Type DIAGNOSTIC_TEST

Participants will undergo magnetoencephalography scan in both resting and tasking state.

Interventions

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Magnetoencephalography

Participants will undergo magnetoencephalography scan in both resting and tasking state.

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Boys aged 6 to 12 years;
* Diagnosis of Autism Spectrum Disorder meeting DSM-5 criteria;
* Intelligence quotient (IQ) score \> 70 (assessed via Wechsler Intelligence Scale for Children or other validated cognitive test);
* Sufficient compliance to participate in MEG experiments.

Exclusion Criteria

* Comorbid neurological disorders, genetic syndromes, or severe developmental disabilities;
* Metallic implants that may interfere with MEG signal acquisition;
* Current use of antipsychotic medications or sedatives.
Minimum Eligible Age

6 Years

Maximum Eligible Age

12 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

Yes

Sponsors

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Beijing X-Magtech Technology Limited

UNKNOWN

Sponsor Role collaborator

Guangzhou Women and Children's Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Guangzhou Women and Children's medical center

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Ye Song, Medical Doctor

Role: CONTACT

+86-020-81886332

Facility Contacts

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Wenhao Zhou, Medical Doctor

Role: primary

+86-020-81886332

Other Identifiers

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447A01

Identifier Type: -

Identifier Source: org_study_id

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