TIPS Block vs. IV Analgesia for Postoperative Pain After Knee Arthroscopy

NCT ID: NCT07046390

Last Updated: 2025-07-01

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 52 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-07-20
• Study Completion Date: 2026-08-20

Brief Summary

In this study participants are aiming to compare triple injection peri-sartorius (TIPS) block versus intravenous analgesia for postoperative analgesia after knee arthroscopy regarding efficacy of pain relief and early ambulation

Detailed Description

Arthroscopic knee surgery is a commonly performed orthopedic procedure due to being minimally invasive and providing early recovery. A significant number of patients have severe postoperative pain despite using small incisions leading to poor quality of postoperative recovery. Currently, multimodal analgesia is a widely used method of pain relief and also to improve patient functionality and satisfaction scores. Systemic opioids and non-steroidal anti-inflammatory drugs (NSAIDs) have been the mainstay for treating postoperative pain after knee surgery. The traditional high-dose opioid approach is associated with increased opioid-related side effects eg: (Nausea ,vomiting and delayed recovery ).NSAIDs are effective as part of a multimodal analgesic approach, but their use can be limited due to concerns regarding coagulopathy or impairment of renal function and GIT side effects.Ultrasound guidance in regional anaesthesia is increasingly being used leading to approaches to the sciatic nerve block, femoral nerve block (FNB), adductor canal block (ACB) and obturator nerve block increasingly motivated as an element of multimodal analgesia regimen in many operations, including knee arthroscopy.Sub sartorial block has been studied for its efficacy in providing analgesia following knee surgeries while preserving quadriceps muscle power. However, misnomers have been prescribed at different locations for different block approaches. TIPS block targets motor-sparing analgesia through injection at three planes ultrsound guided.Study Procedures: Patients will be enrolled in this randomly allocated using computer-based randomization into two groups with (26) patients in each group

• Group 1 (study group number 1) will receive triple injection peri-sartorius (TIPS) block. The block will be done after induction of general anesthesia before skin incision
• Group 2 (study group number 2) (control group )will receive conventional analgesic regimen without having a regional block.

Conditions

Knee Arthroscopic Surgery; Nerve Block

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

tips block group

this group will receive triple injection peri-sartorius (TIPS) block. The block will be done after induction of general anesthesia before skin incision

Group Type: ACTIVE_COMPARATOR

nerve block with bupivacaine 0.25%

Intervention Type: DRUG

0.25% bupivacaine

No intervention

Intervention Type: DRUG

No intervention

control group

control group will receive conventional analgesic regimen without having a regional block.

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

nerve block with bupivacaine 0.25%

0.25% bupivacaine

Intervention Type: DRUG

No intervention

No intervention

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

.Age 18-40 years undergoing knee arthroscopy. .Sex: Both sexes.

.American Society of Anaesthesiologists (ASA) Physical Status Class I and II

Exclusion Criteria

.Declining to give written informed consent. .History of allergy to the medications used in the study. .Contraindications to regional anesthesia (including patient refusal, coagulopathy and local infection).

Psychiatric disorder. .American Society of Anesthesiologists (ASA) Physical Status Class III and IV.

• Patients with body mass index (BMI) >35 kg/m2 .Neurological deficits or mobility-related disorders of the non-operated limb .
• Moderate to severe hepatic , renal diseases and cardiac disease.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Ain Shams University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Ain Shams University

Cairo, , Egypt

Countries

Egypt

Central Contacts

abdelrahman mohammed hanafy, master

Role: CONTACT

abdelrhmanhanafy@med.asu.edu.eg

01114359788

Other Identifiers

FMASU MD24/2024

Identifier Type: -

Identifier Source: org_study_id