Effects of Total and Selective Caries Removal - Requiring or Avoiding Vital Pulp Therapy - on Pulp Vitality and Postoperative Pain in Deep Carious Mature Permanent Teeth: A Split-Mouth Clinical Study

NCT ID: NCT07041905

Last Updated: 2025-07-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-01

Study Completion Date

2026-08-01

Brief Summary

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The effect of selective caries cleaning and total caries cleaning on pulp health and post operative pain in teeth with deep caries will be investigated.

Detailed Description

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Conditions

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Pulp Exposure, Dental Deep Dental Caries

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
Patients and outcome assessors were blinded to the intervention groups. The operator was not blinded due to the visible differences between total and selective caries removal techniques.

Study Groups

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Arm 1

Complete caries excavation

Group Type ACTIVE_COMPARATOR

Total Caries Removal

Intervention Type PROCEDURE

Arm 1: "Total caries removal (complete excavation to hard dentin)"

Arm 2

Partial caries excavation

Group Type EXPERIMENTAL

Selective Caries Removal

Intervention Type PROCEDURE

Partial removal leaving affected dentin near pulp.

Interventions

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Total Caries Removal

Arm 1: "Total caries removal (complete excavation to hard dentin)"

Intervention Type PROCEDURE

Selective Caries Removal

Partial removal leaving affected dentin near pulp.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged ≥15 years with bilateral deep carious mature permanent teeth.
* Positive vitality test (cold sensitivity).
* No spontaneous pain or periapical radiolucency.
* Willingness to attend 6- and 12-month follow-ups

Exclusion Criteria

* Uncontrolled systemic diseases Pregnancy or allergy to dental materials used Teeth with irreversible pulpitis (spontaneous pain, necrosis) Non-restorable teeth (fractures, extensive decay)
Minimum Eligible Age

15 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cukurova University

OTHER

Sponsor Role lead

Responsible Party

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Zehra SUSGUN YILDIRIM

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cukurova University

Adana, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Zehra Zehra Susgun Yıldırım, Principal investigator

Role: CONTACT

0553 454 1123

Facility Contacts

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Cukurova University Cukurova University Faculty of Dentistry

Role: primary

0322 338 73 30

Other Identifiers

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D-SCR-2025-01

Identifier Type: -

Identifier Source: org_study_id

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