Mediterranean Diet Intervention for Maternal Postpartum

NCT ID: NCT07038681

Last Updated: 2025-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

52 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-31

Study Completion Date

2025-12-31

Brief Summary

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The increasing prevalence of obesity during women's reproductive years highlights the need for effective strategies to improve nutritional literacy as a preventive approach to adverse postnatal outcomes.

This study outlines a protocol for a pilot randomized controlled trial assessing the potential of nutritional education sessions promoting the Mediterranean Diet (MedDiet) to improve adherence to this diet and evaluate its effects on cardiometabolic outcomes, namely on cardiac reverse remodeling, glycemic and blood pressure control, as well as on preconception weight recovery and changes in the fecal microbiota composition in pregnant women with obesity, hypertension, and/or diabetes.

Secondarily, this study aims to evaluate how this dietary intervention indirectly interferes with infants' exclusive breastfeeding and the introduction of complementary feeding. It includes a face-to-face session using an eye-catching 13-page manual, followed by five monthly newsletters sent by e-mail. Participants will be monitored at one, six, and twelve months postpartum to evaluate the intervention's effectiveness. Findings from this study will contribute to the development of an evidence-based nutritional education tool designed to improve maternal health outcomes, with potential applicability for both health professionals and pregnant and postpartum women.

Detailed Description

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Conditions

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Postpartum Cardiometabolic Factors Cardiac Reverse Remodeling

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Prospective, randomized, two-treatment, one-period, parallel trial
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Control Group (Standard Hospital Dietary Care)

Since all the pregnant women in this study have at least one of the following risk factors: obesity, diabetes or hypertension, nutritional follow-up is a standard-care procedure in the Portuguese National Health System, therefore the control group receive usual care from the nutritionist in the hospital.

Group Type PLACEBO_COMPARATOR

Control Group (Standard Hospital Dietary Care)

Intervention Type OTHER

The control group will receive standard care from the nutritionist in the hospital.

Mediterranean Diet Intervention Group

In addition to the standard-care follow-up in the Portuguese National Health System, the intervention group will have additionally three approaches within the intervention: i) one face-to-face appointment lasting 10 to 15 minutes conducted by a registered dietitian (3rd trimester: 30 - 35 gestational weeks); ii) a 13-page manual that accompanies the dietary education session, which is provided to each participant; and iii) five monthly newsletters sent via e-mail from two weeks after childbirth until the fifth month postpartum.

Group Type EXPERIMENTAL

Mediterranean Diet Intervention Group

Intervention Type OTHER

In the same way as the control group, the intervention group receives standard nutritional care from the hospital nutritionist, since all the pregnant women have at least one of the following risk factors: obesity, diabetes or hypertension, nutritional - standard-care procedure in the Portuguese National Health System.

Interventions

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Mediterranean Diet Intervention Group

In the same way as the control group, the intervention group receives standard nutritional care from the hospital nutritionist, since all the pregnant women have at least one of the following risk factors: obesity, diabetes or hypertension, nutritional - standard-care procedure in the Portuguese National Health System.

Intervention Type OTHER

Control Group (Standard Hospital Dietary Care)

The control group will receive standard care from the nutritionist in the hospital.

Intervention Type OTHER

Other Intervention Names

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Diet group

Eligibility Criteria

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Inclusion Criteria

* Adult female (\>18 years old)
* Obesity
* Chronic arterial hypertension
* Type 2 diabetes
* Gestational hypertension
* Gestational diabetes

Exclusion Criteria

* Preexisting cardiomyopathy;
* Renal disease;
* Chronic obstructive airway disease;
* Active systemic infection;
* Genetic syndromes;
* Type 1 Diabetes mellitus
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Universidade do Porto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Inês Falcão Pires, PhD

Role: PRINCIPAL_INVESTIGATOR

Universidade do Porto

Locations

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Unidade Local de Saúde de São João

Porto, Viana do Castelo District, Portugal

Site Status RECRUITING

Countries

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Portugal

Central Contacts

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Juliana Morais, Master

Role: CONTACT

220426820 ext. +351

Ana Filipa Ferreira, PhD

Role: CONTACT

220426820 ext. +351

Facility Contacts

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Juliana Morais, Master

Role: primary

225512100 + 962711106 ext. +351

Other Identifiers

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MedMom

Identifier Type: -

Identifier Source: org_study_id

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