COMPARISON OF ERECTOR SPINA PLAN BLOCK AND THORACIC PARAVERTEBRAL BLOCK FOR PERIOPERATIVE ANALGESIA

NCT ID: NCT07021651

Last Updated: 2025-06-15

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Clinical Phase: NA
• Total Enrollment: 60 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-07-10
• Study Completion Date: 2025-08-01

Brief Summary

The primary aim of this study was to compare the postoperative analgesic efficacy of thoracic paravertebral block with erector spinae plane block, which we use in thoracotomy surgeries. Secondary aims were to compare these groups in terms of Riker Agitation-Sedation Scale (RASS) scores, postoperative complications, postoperative opioid consumption, and patient satisfaction.

Conditions

Paravertebral Block

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: DOUBLE

Study Groups

Erektor spina plan block

The local anesthetic is injected into the fascial plane between the erector spinae muscle and the transverse processes of the vertebrae. This allows the anesthetic to spread cranially and caudally, affecting multiple spinal nerves

Group Type: ACTIVE_COMPARATOR

Erector Spinae Plane (ESP) block admistring

Intervention Type: PROCEDURE

In the ESPB group, the probe was placed longitudinally at the level of the T5 transverse process, 2-3 cm lateral from the midline. The muscles were visualized superior to the transverse process ; then, the needle was inserted in the craniocaudal direction using the in-plane technique. A dose of 2 mL normal saline were injected into the two layers of the interfacial area under the erector spinae muscle, and the proper injection site was confirmed. After visualizing the linear spread of saline in the fascial plane, 20 mL of 0.25% bupivacaine was injected there for the block.

Toracik paravertebral block

The local anesthetic is injected into the paravertebral space, which is bordered by the vertebral bodies, intervertebral discs, parietal pleura, and superior costotransverse ligament. This space contains the spinal nerves, sympathetic chain, and intercostal vessels

Group Type: ACTIVE_COMPARATOR

Thoracic Paravertebral Block administring

Intervention Type: PROCEDURE

In the TPVB group, the probe was placed 2-3 cm laterally and vertically of the T5 spinous process. Once the transverse process, corresponding paravertebral space, internal intercostal membrane, and pleura was identified , the needle was inserted in the lateromedial direction using the in-plane technique. After confirmation of pleural displacement with 2 mL saline, 20 mL of 0.25% bupivacaine was administered for the block.

Interventions

Erector Spinae Plane (ESP) block admistring

In the ESPB group, the probe was placed longitudinally at the level of the T5 transverse process, 2-3 cm lateral from the midline. The muscles were visualized superior to the transverse process ; then, the needle was inserted in the craniocaudal direction using the in-plane technique. A dose of 2 mL normal saline were injected into the two layers of the interfacial area under the erector spinae muscle, and the proper injection site was confirmed. After visualizing the linear spread of saline in the fascial plane, 20 mL of 0.25% bupivacaine was injected there for the block.

Intervention Type: PROCEDURE

Thoracic Paravertebral Block administring

In the TPVB group, the probe was placed 2-3 cm laterally and vertically of the T5 spinous process. Once the transverse process, corresponding paravertebral space, internal intercostal membrane, and pleura was identified , the needle was inserted in the lateromedial direction using the in-plane technique. After confirmation of pleural displacement with 2 mL saline, 20 mL of 0.25% bupivacaine was administered for the block.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Patients who will undergo thoracotomy and are between the ages of 18-65
• have American Society of Anesthesiologists (ASA) risk classification I-II will be included in the study.

Exclusion Criteria

• Patients who did not agree to participate in the study,
• had an infection in the application area,
• had coagulopathy,
• were morbidly obese (Body mass index (BMI)>35),
• had drug allergy,
• had chronic pain, long-term opioid use, psychiatric illness history, and required emergency surgery were excluded from the study.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Hülya Tosun Söner

Anesthesiology and Reanimation Spesialist

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Health Sciences University Gazi Yaşargil Training and Research Hospital

Kayapınar, Di̇yarbakir, Turkey (Türkiye)

Countries

Turkey (Türkiye)

Central Contacts

Hülya Tosun Söner, doktor

Role: CONTACT

hulyatosunsoner@hotmail.com

+905352792102

Facility Contacts

Role: primary

hulyatosunsoner@hotmail.com

Other Identifiers

CEM

Identifier Type: -

Identifier Source: org_study_id