Glucose Empowerment Through Monitoring and Social Support in Pregnancy

NCT ID: NCT07009704

Last Updated: 2025-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-07-01

Study Completion Date

2026-07-31

Brief Summary

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The purpose of the research is to learn whether wearing a continuous glucose monitor that shows blood glucose levels in real time on a smart phone app and participating in a group chat with other research participants will help participants keep a healthy blood glucose level during pregnancy.

High levels of blood glucose during pregnancy can lead to health problems during and after pregnancy. It may also increase the risk for health problems for the developing baby.

The investigators think our program might be a new way to help some people maintain a healthy blood glucose level during pregnancy. When pregnant people know their blood glucose levels are high, they can do things like exercise or drink water to bring their blood glucose levels down. They can also learn what foods to eat to maintain healthy blood glucose levels, and what foods to avoid. The investigators think being in a group chat with other pregnant individuals will allow participants to support and learn from each other. Pregnant individuals should also work with their healthcare providers to manage their blood glucose levels.

Detailed Description

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Conditions

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Pregnancy, Complications Gestational Diabetes

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants will be randomly assigned to one of two groups. Group 1 will receive real-time continuous glucose monitoring plus mobile-based social support. Group 2 will only receive real-time continuous glucose monitoring.
Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Group 1- Group chat intervention

Participants in group 1 will be randomized to wear a real-time continuous glucose monitor for 14 days and participate in a secure mobile-based group chat where they will provide and receive social support for glucose management. Participants will be in the group chat for 60 days.

Group Type EXPERIMENTAL

Mobile-based social support

Intervention Type BEHAVIORAL

Participants will be invited to join an encrypted group chat where they will be encouraged to provide and receive social support related to glucose management during early pregnancy. Other study participants and study team members will be in the group chat.

Real-time continuous glucose monitoring

Intervention Type BEHAVIORAL

Participants will receive a real-time continuous glucose monitor that pairs with an existing smartphone app that shows minute-by-minute glucose levels and records glucose levels in 5 minute increments.

Group 2- No group chat intervention

Participants in group 2 will be randomized to wear a real-time continuous glucose monitor for 14 days.

Group Type EXPERIMENTAL

Real-time continuous glucose monitoring

Intervention Type BEHAVIORAL

Participants will receive a real-time continuous glucose monitor that pairs with an existing smartphone app that shows minute-by-minute glucose levels and records glucose levels in 5 minute increments.

Interventions

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Mobile-based social support

Participants will be invited to join an encrypted group chat where they will be encouraged to provide and receive social support related to glucose management during early pregnancy. Other study participants and study team members will be in the group chat.

Intervention Type BEHAVIORAL

Real-time continuous glucose monitoring

Participants will receive a real-time continuous glucose monitor that pairs with an existing smartphone app that shows minute-by-minute glucose levels and records glucose levels in 5 minute increments.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Pregnant (\<20w0d)
* At least 18 years to 45 years old
* BMI \>25, personal history of GDM, or first-degree family member with type II diabetes
* Comfortable conversing in English
* Own a smartphone and willing to use the CGM app and Signal
* Receiving prenatal care and planning to deliver at Tufts Medicine (Boston)
* Signed the consent form
* Currently located in the United States

Exclusion Criteria

* Current pregnancy a multiple gestation (e.g., twins)
* Smoked during this current pregnancy
* Active hepatitis or HIV infection
* Current pregnancy have any documented fetal congenital anomalies
* Current history of heroin, cocaine, crack, LSD, or methamphetamines
* Current history of alcohol abuse
* Previous gastric bypass
* Shift work that alters the sleep/wake periods
* Have known rheumatological or chronic inflammatory state (i.e., arthritis, inflammatory bowel disease)?
* Chronic illnesses, including diabetes and dialysis, that require regular medication use
* Uncontrolled hypothyroidism
* Known culture of positive chorioamnionitis?
* An adult who is unable to consent (e.g., cognitively impaired adults)
* Ward of the state
* Unable to read or write English
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

Sponsor Role collaborator

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NIH

Sponsor Role collaborator

Tufts Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Tufts Medical Center

Boston, Massachusetts, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Larissa Calancie, PhD

Role: CONTACT

(617) 636-0976

Facility Contacts

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Larissa Calancie

Role: primary

Other Identifiers

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K12HD092535

Identifier Type: NIH

Identifier Source: secondary_id

View Link

K12AR084217

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY00005143

Identifier Type: -

Identifier Source: org_study_id

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