Educational Kinesiology Program's Effect on Cognition, Manual Dexterity and Bimanual Coordination in MS Patients

NCT ID: NCT07002151

Last Updated: 2025-06-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 36 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-01-10
• Study Completion Date: 2025-05-10

Brief Summary

the purpose of this study was to evaluate the usefulness of educational kinesiology program to improve cognitive impairement, manual dexterity and bimanual coordination in patients with relapsing remitting multiple sclerosis. the study evaluated some domain of cognition as (attention & concentration, figural memory, reaction behavior and logical reasoning) manual dexterity and bimanual coordination were also evaluated of individuals with multiple sclerosis who went through the traditional as compared to others who used educational kinesiology training as part of their therapy.

Detailed Description

Multiple sclerosis (MS) is a chronic non-curative immune inflammatory demyelinating disease mainly affects the Central Nervous System. Cognitive deficits are common in MS and affect patients at all stages of the disease-including the early stage. There was a negative correlation between the employment of MS patients and their cognitive impairment assessed by information processing speed, memory, and executive function. Currently, the recommended treatments for cognitive dysfunction and depression in people with MS are cognitive retraining and cognitive behavioural therapy, respectively. Both of these approaches are time-consuming and are often unavailable away from major treatment centres. The common clinical signs of the disease include motor and sensory deficits, cerebellar symptoms, fatigue, and/or vision problems, which can impact manipulative dexterity in 76% of the population with MS. Often, patients also present bilateral impairments.Educational kinesiology program is the original 26 movements. The movements which are naturally done during the first years of life when learning coordinated the eyes, ears, hands and whole body are recalled by these activities. The principle behind Educational kinesiology program is that moving with intention leads to optimal learning. Educational kinesiology program has a beneficial effect on cognitive function and combines movement of the feet, hands in the optimization of left and right brain functions so as to improve cognitive function that were damaged or decrease.

Conditions

Relapsing-remitting Multiple Sclerosis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

study group

experimental arm was recieved educational kinesiology program and conventional upper extremity coordination exercises as intervention.Respondents were explained about the Educational kinesiology program.by the therapist. The exercise program was given three times weekly for four weeks. Duration of the session was15 min ), the patients did 5 exercises, each exercise was done for 3 minutes,when patient felt fatigue during performing the exercise he or she stopped then continued after relaxation till reaching 3 min for each one . All exercises were done from sitting position.

Group Type: EXPERIMENTAL

educational kinesiology training program intervention for study group

Intervention Type: OTHER

The Educational kinesiology program were included : (Cross crawl) Sit or stand and with the right-hand elbow touch the left knee and vice versa. (The owl) Bring one hand up to the opposite shoulder and hold a pinch around the trapezius muscle between the neck and shoulder. the thumb should be on one side of the muscle and the other fingers clasping around the other side. Turn the head to the same side as thehand is gripping and take a deep breath. Slowly exhale as bringing the head gently around to the other side. Repeat this movement one more time. (The arm activation) Hold one arm next to the ear. Exhale gently while activating the muscles by pushing the arm against the other hand in four directions (front, back, in and away). (The Energizer) Place the head on the desk in front exhale and inhale while coming up and try to hyperextend the neck carefully. (cook's hook-up) put the left ankle over your right knee. Next, hook the right hand around the left ankle.

conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

Intervention Type: OTHER

Bimanual coordination,Hand-arm coordination ,Drinking \& Strength training

control group

received conventional physical therapy program in form of upper extremities coordination training

Group Type: ACTIVE_COMPARATOR

conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

Intervention Type: OTHER

Bimanual coordination,Hand-arm coordination ,Drinking \& Strength training

Interventions

educational kinesiology training program intervention for study group

The Educational kinesiology program were included : (Cross crawl) Sit or stand and with the right-hand elbow touch the left knee and vice versa. (The owl) Bring one hand up to the opposite shoulder and hold a pinch around the trapezius muscle between the neck and shoulder. the thumb should be on one side of the muscle and the other fingers clasping around the other side. Turn the head to the same side as thehand is gripping and take a deep breath. Slowly exhale as bringing the head gently around to the other side. Repeat this movement one more time. (The arm activation) Hold one arm next to the ear. Exhale gently while activating the muscles by pushing the arm against the other hand in four directions (front, back, in and away). (The Energizer) Place the head on the desk in front exhale and inhale while coming up and try to hyperextend the neck carefully. (cook's hook-up) put the left ankle over your right knee. Next, hook the right hand around the left ankle.

Intervention Type: OTHER

conventional upper extremities coordination training for both arms experimental and comparator (study and control) groups

Bimanual coordination,Hand-arm coordination ,Drinking \& Strength training

Intervention Type: OTHER

Other Intervention Names

brain gym exercises

Eligibility Criteria

Inclusion Criteria

• Male or female aged from 18-50 years.
• Patients with relapsing remitting MS (RRMS).
• EDSS scores for (RRMS) is ranging from 2.5 to 5.5 with a pyramid function score less than 2.
• Gave their oral and written consent to participate in the training.
• Adequate vision and hearing for completion of the study protocol, as indicated by the ability to follow written and oral instructions during screening.
• Stable medical condition.

Exclusion Criteria

• Patients with communication problems.
• Patients with a history of previous neurologic diseases or disorders.
• Patients with other types of MS.
• In co-operative patients.
• Unhealed fracture, contracture, pressure sores that might interfere with training.
• Untreated psychiatric disorders or ongoing drug abuse.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

mona abo-elabbas ahmed

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

eman s fayez, doctorate

Role: STUDY_DIRECTOR

Locations

Faculty of Physicaltherapy

Cairo, , Egypt

Countries

Egypt

References

Alharthi HM, Almurdi MM. Association between cognitive impairment and motor dysfunction among patients with multiple sclerosis: a cross-sectional study. Eur J Med Res. 2023 Mar 2;28(1):110. doi: 10.1186/s40001-023-01079-6.

Reference Type: BACKGROUND

PMID: 36864515 (View on PubMed)

Lyle KB, Dombroski BA, Faul L, Hopkins RF, Naaz F, Switala AE, Depue BE. Bimanual coordination positively predicts episodic memory: A combined behavioral and MRI investigation. Brain Cogn. 2017 Nov;118:71-79. doi: 10.1016/j.bandc.2017.07.009. Epub 2017 Aug 9.

Reference Type: BACKGROUND

PMID: 28800429 (View on PubMed)

Other Identifiers

effect of EKP on cognition

Identifier Type: -

Identifier Source: org_study_id