Medical Follow-up of New Cases of Polyarthritis in Children and Young Adults

NCT ID: NCT07000916

Last Updated: 2025-06-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-09-11

Study Completion Date

2028-03-31

Brief Summary

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Population:

Juvenile idiopathic arthritis (JIA), rheumatoid arthritis (RA) and seronegative / psoriatic / undifferentiated arthritis (UA), systemic lupus erythematosus (SLE) or diffuse systemic sclerosis dSS).

Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

These 5 cohorts will be subject to standardized clinical monitoring.

Detailed Description

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This study is proposed by the Rheumatology and Pediatrics departments of the 3 French-speaking Universities.

The first objective will be to include a progressive number of new young patients (≤ 50 years) in order to optimize and standardize care and clinical response objectives. The number of 25% of new incident cases will be sought with an increase of 20% each year during the 5 to 10 years of this project.

Population: JIA, RA/UA, SLE, dSS (American Congres of Rheumatology criteria). Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

These 5 cohorts will be subject to standardized clinical monitoring and specific objectives that will make it possible to analyze the number of patients with a good control of the disease and/or a clinical remission, defined according to the international criteria.

Conditions

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Juvenile Idiopathic Arthritis Rheumatoid Arthritis Psoriatic Arthritis Systemic Lupus Erythematosus Diffuse Systemic Sclerosis Seronegative Arthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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juvenile idiopathic arthritis (JIA)

aged \<= 16 y.o. recent diagnosis of JIA and DMARDs treatment-naive patients; aged \<18 y.o. recent diagnosis of JIA

No interventions assigned to this group

rheumatoid arthritis (RA)

aged =\>18; =\< 50 y.o. recent diagnosis of RA and DMARDs treatment-naive patients

No interventions assigned to this group

diffuse systemic sclerosis (dSS)

aged =\>18; =\< 50 y.o. recent diagnosis of dSS and DMARDs treatment-naive patients

No interventions assigned to this group

seronegative arthritis (UA)

aged =\>18; =\< 50 y.o. recent diagnosis of UA and DMARDs treatment-naive patients

No interventions assigned to this group

systemic lupus erythematosus (SLE)

aged =\>18; =\< 50 y.o. recent diagnosis of SLE and DMARDs treatment-naive patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Diagnosis of juvenile idiopathic arthritis, rheumatoid arthritis and seronegative / psoriatic / undifferentiated arthritis, systemic lupus erythematosus or diffuse systemic sclerosis (ACR criteria).
* Naïve to basic treatment OR treated for ≤ 3 months; except for patients with JIA.

Exclusion Criteria

* Treated for \> 3 months
* \> 50 years old
Minimum Eligible Age

2 Years

Maximum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Université Catholique de Louvain

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Patrick Durez, Pr

Role: STUDY_DIRECTOR

UCLouvain - IREC

Locations

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UCLouvain

Brussels, , Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Patrick Durez

Role: CONTACT

+32 02 764 53 89

Facility Contacts

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Patrick Durez

Role: primary

Tatiana Sokolova

Role: backup

Other Identifiers

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Cap 48 polyarthrite

Identifier Type: -

Identifier Source: org_study_id

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