Impact of a Targeted 8-Week Exercise Program on Pain Measures and Isokinetic Muscle Strength in Females With Patellofemoral Pain Syndrome

NCT ID: NCT06993350

Last Updated: 2025-07-28

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 30 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-03-02
• Study Completion Date: 2025-04-30

Brief Summary

Patellofemoral pain syndrome (PFPS) is condition characterized by anterior knee pain that predominantly affects young and physically active females. The etiology of PFPS is multifactorial, involving biomechanical, muscular, and neuromuscular factors that contribute to altered patellar tracking and increased pain sensitivity.

Detailed Description

This study will employ a randomized controlled trial (RCT) design to evaluate the effects of a targeted 8-week exercise program on pain measures and isokinetic muscle strength in females with PFPS. Thirty female patients diagnosed with PFPS will be recruited based on predefined inclusion and exclusion criteria. Participants will be randomly assigned into two groups: an intervention group receiving the targeted exercise program, and a control group will not receive any intervention.The intervention group will undergo a supervised, structured exercise program lasting 8 weeks, focusing on strengthening the hip and knee muscles, improving neuromuscular control, and addressing pain sensitivity. Sessions will be conducted multiple times per week under professional supervision. Outcome measures will include pain measures, assessed through validated tools such as pressure pain threshold and pain intensity measured by VAS scale and isokinetic muscle strength of knee and hip muscles, measured by isokinetic dynamometry at the Biodex isokinetic Laboratory at the Faculty of Physical Therapy, Cairo University.

Conditions

Patellofemoral Pain Syndrome

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: QUADRUPLE

Study Groups

group A (patients with PFPS)

patients receive specific weight bearing program known as weight bearing exercise for better balance program

Group Type: OTHER

experimental group

Intervention Type: OTHER

eight weeks of targeted weight bearing program

control group

patient will not receive any intervention

Group Type: NO_INTERVENTION

No interventions assigned to this group

Interventions

experimental group

eight weeks of targeted weight bearing program

Intervention Type: OTHER

Other Intervention Names

weight bearing program

Eligibility Criteria

Inclusion Criteria

Eligible participants will present with clinically diagnosed anterior knee pain exacerbated by activities such as stair climbing, squatting, or prolonged sitting, with a pain duration of at least three months to ensure chronicity. All participants will possess adequate intellectual and cognitive abilities to comprehend and follow exercise instructions, and they will provide informed consent prior to enrollment.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 40 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Cairo University

OTHER

Sponsor Role: lead

Responsible Party

Azza Mohammed

Prof. Dr

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Faculty of Physical Therapy, Cairo University

Giza, , Egypt

Countries

Egypt

Other Identifiers

faculty of physical therapy

Identifier Type: REGISTRY

Identifier Source: secondary_id

Faculty of Physical Therapy

Identifier Type: -

Identifier Source: org_study_id