Risk Assessment of Mild Traumatic Brain Injury in Military Training

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-11-04

Study Completion Date

2026-09-30

Brief Summary

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The SNIPER-TBI study aims to identify and quantify the risk of mild traumatic brain injury (mTBI) in soldiers of the Czech Armed Forces during specific high-risk training activities, including parachute jumps, high-caliber firearms shooting, artillery blasts, and Close Quarters Battle (CQB) exercises. The study will utilize both diagnostic biomarker analysis and experimental biomechanical measurements to assess the physiological impact of these activities on brain health. The ultimate goal is to reduce mTBI incidence, improve operational readiness, and extend the active service duration of soldiers through targeted preventive measures.

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Detailed Description

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The SNIPER-TBI study aims to quantify the risk of mild traumatic brain injury (mTBI) in Czech Armed Forces soldiers during high-risk training activities, including parachute jumps, high-caliber firearms shooting, artillery blasts, and Close Quarters Battle (CQB) exercises. The study combines diagnostic biomarker analysis (GFAP, UCH-L1) and experimental biomechanical measurements using wearable sensors and high-speed cameras. These data will provide critical insights into the forces exerted on the brain during training and help establish exposure limits to minimize long-term neurological impairment. The results will guide the development of protective strategies and enhance soldier readiness.

Conditions

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Trauma, Brain

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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High-Risk Military Training Exposure

Active-duty soldiers participating in high-risk training activities, including parachute jumps, high-caliber firearms shooting, artillery blasts, and Close Quarters Battle (CQB) exercises. Participants will undergo real-time biomechanical measurement and biomarker analysis to assess mild traumatic brain injury (mTBI) risk.

Diagnostic biomarker analysis (GFAP, UCH-L1) Real-time biomechanical monitoring (accelerometers, high-speed cameras)

Group Type EXPERIMENTAL

Quantification of mild trauma brain injury risk

Intervention Type DIAGNOSTIC_TEST

Measure the incidence and severity of mTBI among soldiers engaged in high-risk training activities. (e.g. parachute jumps, high-caliber firearms shooting, artillery fire, explosions). Concentration of brain injury biomarkers (GFAP, UCH-L1) in blood samples collected within 24 hours post-exposure

Biomechanical Analysis of Head Impact Forces

Intervention Type OTHER

Evaluate the mechanical forces experienced by soldiers during high-risk activities using wearable accelerometers and high-speed video analysis. Peak head acceleration (g-force) and pressure wave analysis during training activities.