Iatrogenic Deficiencies in ICU Patients With Prolonged Continuous Renal Replacement Therapy

NCT ID: NCT06983197

Last Updated: 2025-05-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-06-01

Study Completion Date

2029-12-31

Brief Summary

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ICU patients are recruited after at least 5 days treatment with continuous renal replacement therapy. Blood samples are drawn at time of recruitment and then every 3-5 days until ceseation of renal replacement therapy.

Samples will be analyzed for concentrations of trace elements, vitamins and amino acids.

10 adult ICU patients treated for two weeks without renal replacement therapy will be sampled at one time point to serve as controls.

Detailed Description

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Conditions

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Acute Kidney Injury

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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CRRT patients

Patients, all ages, that receive CRRT for at least five days.

blood test

Intervention Type DIAGNOSTIC_TEST

Blood samples are drawn every 3-5 days in the RRT group but only once in the control group

Non-CRRT patient

Adult patients, \>17 yo, treated in the ICU for 10-15 days without renal replacement therapy

blood test

Intervention Type DIAGNOSTIC_TEST

Blood samples are drawn every 3-5 days in the RRT group but only once in the control group

Interventions

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blood test

Blood samples are drawn every 3-5 days in the RRT group but only once in the control group

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* CRRT more than 5 days


\- ICU care 10-15 days without any dialysis treatment

Exclusion Criteria

* N/A
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jonathan Grip

MD, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jonathan Grip, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Karolinska University Hospital

Central Contacts

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Jonathan Grip, MD, PhD

Role: CONTACT

+46 73 623 09 06

Kristina Kilsand, Research nurse

Role: CONTACT

+46 8 123 810 03

Other Identifiers

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2024-07642-01

Identifier Type: -

Identifier Source: org_study_id

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