Electrical Cardiometry in Management of Acute Heart Failure

NCT ID: NCT06982560

Last Updated: 2025-05-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-01

Study Completion Date

2024-12-31

Brief Summary

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The goal of this clinical trial is to assess if electrical cardiometry (EC) could help in managing acute heart failure (AHF). The main questions it aims to answer are:

1. Is there effect of use of cardiometry on rate of use of vasopressors, vasodilators and inotropes?
2. is there effect of use of cardiometry on mortality and hospital length of stay?

Researchers compared cardiometry to traditional methods like clinical examination, lung ultrasound and inferior vena cava.

Participants were divided into two groups, one managed by cardiometry and the other by traditional methods, then followed till improvement or death and compared regarding use of medications, length of stay and mortality

Detailed Description

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The purpose of the research is to assess the role of electrical cardiometry in hemodynamic monitoring in studied cases with acute heart failure to guide treatment.

This is a prospective controlled research that involved fifty patients, diagnosed with acute heart failure and admitted to critical care units at Alexandria University Hospitals, patients were divided into 2 groups:

Group A: was assessed by traditional methods which include: clinical examination including chest auscultation and systolic blood pressure measurement, lung ultrasound and inferior vena cava assessment and managed according to the results of these parameters.

Group B: was assessed by electrical cardiometry parameters as cardiac output, thoracic fluid content (TFC) and systemic vascular resistance (SVR) and was managed as following: inotropes up and down titration according to cardiac output readings, use of vasopressors or vasodilators according to SVR readings, doses of diuretics were modified according to TFC readings.

Conditions

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Acute Heart Failure (AHF)

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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Group A: traditional group

traditional methods like clinical examination, lung ultrasound, inferior vena cava

Group Type PLACEBO_COMPARATOR

traditonal methods

Intervention Type OTHER

clinical examination, lung ultrasound, inferior vena cava

Group B: cardiometry group

use of cardiometry parameters like cardiac output, thoracic fluid content and systemic vascular resistance

Group Type EXPERIMENTAL

electrical cardiometry

Intervention Type DEVICE

use of cardiometry parameters as cardiac output, thoracic fluid content, systemic vascular resistance

Interventions

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electrical cardiometry

use of cardiometry parameters as cardiac output, thoracic fluid content, systemic vascular resistance

Intervention Type DEVICE

traditonal methods

clinical examination, lung ultrasound, inferior vena cava

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* acute heart failure

Exclusion Criteria

* pregnant females, atrial fibrillation, severe valvular diseases, skin lesions in thoracic area, large pleural effusion
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Mohammed R Elsalamouny, MD

Role: PRINCIPAL_INVESTIGATOR

Lecturer of Critical Care Medicine, Alexandria University

Locations

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Alexandria University Hospitals

Alexandria, Alexandria Governorate, Egypt

Site Status

Countries

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Egypt

References

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Shaheen, Mostafa Mohamed, Ahmed Said Elgebaly, Ghada Fouad Elbaradey, and Amira Mahfouz Alqablawi. 2022. "Fluid Management Using Cardiometry in ARDS Patients". Journal of Advances in Medicine and Medical Research 34 (11):21-27. https://doi.org/10.9734/jammr/2022/v34i1131360.

Reference Type BACKGROUND

Paranjape VV, Henao-Guerrero N, Menciotti G, Saksena S, Agostinho M. Agreement between Electrical Cardiometry and Pulmonary Artery Thermodilution for Measuring Cardiac Output in Isoflurane-Anesthetized Dogs. Animals (Basel). 2023 Apr 21;13(8):1420. doi: 10.3390/ani13081420.

Reference Type BACKGROUND
PMID: 37106987 (View on PubMed)

Abdou , Noura, Heba Elmahdy, Osama Tolba, Nihal Shihab, Asmaa Elmesiry, and Mohammed Rowisha. 2023. "Electrical Cardiometry Versus Echocardiography in Assessment of Hemodynamic Status in Preterm Neonates With Septic Shock". Journal of Advances in Medicine and Medical Research 35 (20):144-55. https://doi.org/10.9734/jammr/2023/v35i205184.

Reference Type BACKGROUND

Liu YH, Dhakal BP, Keesakul C, Kacmarek RM, Lewis GD, Jiang Y. Continuous non-invasive cardiac output monitoring during exercise: validation of electrical cardiometry with Fick and thermodilution methods. Br J Anaesth. 2016 Jul;117(1):129-31. doi: 10.1093/bja/aew156. No abstract available.

Reference Type BACKGROUND
PMID: 27317712 (View on PubMed)

Related Links

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Other Identifiers

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0107959

Identifier Type: -

Identifier Source: org_study_id

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