Chronic Neck Pain and Central Sensizitation

NCT ID: NCT06976398

Last Updated: 2025-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

64 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-05-08

Study Completion Date

2026-03-15

Brief Summary

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Chronic neck pain is one of the musculoskeletal pain problems that can cause chronic disability. It is emphasised that individuals with chronic neck pain have difficulty during different activities in their daily lives, and that this problem is a very common health problem that can lead to disability. In the case of chronic neck pain, changes in the pain threshold cause central sensitisation and individuals become more sensitive to pain stimuli. This situation can affect the processing of proprioceptive information and lead to deterioration in proprioceptive perception. This situation leads to perceptual problems in body and neck awareness. Therefore, examining the relationship between the relevant parameters is important in the rehabilitation process. In this context, the aim of the study is to examine the relationship between body awareness and pain, central sensitisation, disability and proprioception in patients with chronic non-specific neck pain.

Detailed Description

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Chronic neck pain is a common pain problem related to the musculoskeletal system and can lead to permanent (chronic) disability over time. In approximately 50-85% of individuals with neck pain, complaints do not completely improve despite treatment, causing the pain to become chronic. Individuals with chronic neck pain have difficulty performing various activities in their daily lives, and this negatively affects their quality of life. Proprioceptive feedback in the neck region, that is, sensory information that allows the body to perceive its position in space, is very important for proper control of head and neck movements. However, chronic pain can lead to a condition called central sensitization. In this case, the individual's pain threshold decreases and they become more sensitive to stimuli that would normally not cause pain. This increased sensitivity can make it difficult for the brain to process proprioceptive information correctly, which can lead to impairments in body and neck awareness. Therefore, investigating the relationship between body awareness and pain level, central sensitization, disability status and proprioception in individuals with chronic non-specific neck pain is of great importance in terms of developing an effective rehabilitation program.

Conditions

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Neck Pain

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Higher sensitization

It will consist of patients who exceed the cut-off score according to the central sensitization scale score.

No interventions assigned to this group

Normal sensitization

It will consist of patients with a central sensitization scale score lower than the cut-off score.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Being between the ages of 18-65
* Being diagnosed with chronic non-specific neck pain by a doctor
* Being willing to participate in the study

Exclusion Criteria

* Having psychological disorders, mental disorders, cancer and severe depression
* Having a history of traumatic injury
* Having a history of primary or metastatic spinal malignancy, spinal fracture
* Having a neurological disease (Hemiplegia, Multiple Sclerosis, Parkinson's, etc.)
* Having been diagnosed with advanced osteoporosis
* Having a history of surgical intervention or acute infection in the cervical region
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Karabuk University

OTHER

Sponsor Role lead

Responsible Party

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Musa Güneş

Principal Investigator, PhD

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Musa Gunes, PhD

Role: STUDY_DIRECTOR

Karabuk University

Melek Turan

Role: PRINCIPAL_INVESTIGATOR

Karabuk University

Duygu Çataloluk

Role: PRINCIPAL_INVESTIGATOR

Karabuk University

Aydın Sinan Apaydın, PhD

Role: PRINCIPAL_INVESTIGATOR

Karabuk University

Locations

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Karabuk University

Karabük, , Turkey (Türkiye)

Site Status RECRUITING

Countries

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Turkey (Türkiye)

Central Contacts

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Musa Gunes, PhD

Role: CONTACT

05315132482

Facility Contacts

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Musa Güneş, MsC

Role: primary

+905315132482

References

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van der Maas LC, Koke A, Bosscher RJ, Twisk JW, Janssen TW, Peters M. Body Awareness as an Important Target in Multidisciplinary Chronic Pain Treatment: Mediation and Subgroup Analyses. Clin J Pain. 2016 Sep;32(9):763-72. doi: 10.1097/AJP.0000000000000320.

Reference Type BACKGROUND
PMID: 26550959 (View on PubMed)

Williams DA. Phenotypic Features of Central Sensitization. J Appl Biobehav Res. 2018 Jun;23(2):e12135. doi: 10.1111/jabr.12135. Epub 2018 Jun 27.

Reference Type BACKGROUND
PMID: 30479469 (View on PubMed)

Wand BM, Catley MJ, Rabey MI, O'Sullivan PB, O'Connell NE, Smith AJ. Disrupted Self-Perception in People With Chronic Low Back Pain. Further Evaluation of the Fremantle Back Awareness Questionnaire. J Pain. 2016 Sep;17(9):1001-12. doi: 10.1016/j.jpain.2016.06.003. Epub 2016 Jun 18.

Reference Type RESULT
PMID: 27327235 (View on PubMed)

Other Identifiers

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Karabuk-2281

Identifier Type: -

Identifier Source: org_study_id

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