Nurse-Led Telehealth for Gout

NCT ID: NCT06971146

Last Updated: 2025-09-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-10-01

Study Completion Date

2027-08-01

Brief Summary

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The aim of this clinical trial is to evaluate whether nurse-led telehealth support helps individuals with gout better manage their condition and adhere to urate-lowering medication after discharge from a rheumatology clinic.

Eligible patients will be recruited from five rheumatology departments in the Central Denmark Region after achieving two consecutive target serum urate levels-below 0.36 mmol/L, or below 0.30 mmol/L for patients with tophi.

Participants will be adults with gout who meet specific medical criteria, are taking medications such as allopurinol or Adenuric, and are able to read and write Danish.

Participants will be randomly assigned to one of two groups:

* Intervention group: nurse-led telehealth support.
* Control group: usual care with follow-up by their general practitioner.

The primary goal is to support patients in maintaining healthy uric acid levels after 52 weeks.

Participants in the nurse-led group have the option to choose from four support options:

I1: App-Based Support - an app provides information and reminders. I2: Letter Reminders - messages are sent via digital or postal mail. I3: Text Reminders - SMS messages are sent every three months. I4: Phone Support - nurses call three times a year to check in.

Detailed Description

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Conditions

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Health Literacy Gout Arthritis Gout Initiating Urate-loweringUrate-lowering Therapy Telehealth Digital Health Adherence

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A multicenter, randomized controlled superiority trial with two parallel groups
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Nurse-led self-management support

Group Type EXPERIMENTAL

Nurse-Led Self-Management Support

Intervention Type OTHER

The intervention offers four distinct support options. Patients are free to choose the option that best suits their preferences and needs.

I1: App-Based Monitoring - Patients receive an app that provides relevant health information, including short educational videos, images, and other resources. Every three months, the app sends a pop-up reminder.

I2: Reminder by Letter - Patients receive a friendly reminder every three months via e-Boks or postal mail (for those without e-Boks access) encouraging continued treatment adherence.

I3: SMS Reminder - Patients receive a text message every three months to remind them to continue their treatment.

I4: Phone Call Check-In - A nurse contacts the patient by phone three times per year at scheduled intervals to provide support and ensure they remain on track with their treatment.

GP-follow up

Group Type ACTIVE_COMPARATOR

GP-follow up

Intervention Type OTHER

Patients in the control group will be discharged from the hospital and continue with routine care provided by their general practitioner (GP). The GP will receive a discharge letter outlining the recommended treatment plan. In addition, patients will receive a letter containing key information about their condition, along with a recommendation to consult their GP annually for ongoing disease monitoring.

Interventions

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Nurse-Led Self-Management Support

The intervention offers four distinct support options. Patients are free to choose the option that best suits their preferences and needs.

I1: App-Based Monitoring - Patients receive an app that provides relevant health information, including short educational videos, images, and other resources. Every three months, the app sends a pop-up reminder.

I2: Reminder by Letter - Patients receive a friendly reminder every three months via e-Boks or postal mail (for those without e-Boks access) encouraging continued treatment adherence.

I3: SMS Reminder - Patients receive a text message every three months to remind them to continue their treatment.

I4: Phone Call Check-In - A nurse contacts the patient by phone three times per year at scheduled intervals to provide support and ensure they remain on track with their treatment.

Intervention Type OTHER

GP-follow up

Patients in the control group will be discharged from the hospital and continue with routine care provided by their general practitioner (GP). The GP will receive a discharge letter outlining the recommended treatment plan. In addition, patients will receive a letter containing key information about their condition, along with a recommendation to consult their GP annually for ongoing disease monitoring.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* ≥18 years old
* Fulfills ACR/EULAR 2015 Gout Classification Criteria
* Estimated Glomerular Filtration Rate (e-GFR) \>30 ml/min
* Prescribed Allopurinol or Adenuric, and achieved two consecutive serum urate levels of two consecutive serum urate levels of ≤0.30 mmol/l for patients with tophi and ≤0.36 mmol/L for patients without tophi
* Have sufficient Danish reading and writing skills to understand information and complete questionnaires.

Exclusion Criteria

• Cognitively impaired, unable to understand or provide informed consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aarhus University Hospital

OTHER

Sponsor Role collaborator

Regionshospitalet Silkeborg

OTHER

Sponsor Role collaborator

Gødstrup Hospital

OTHER

Sponsor Role collaborator

Randers Regional Hospital

OTHER

Sponsor Role collaborator

Regionshospitalet Horsens

OTHER

Sponsor Role collaborator

University of Aarhus

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Aarhus University Hospital

Aarhus, , Denmark

Site Status RECRUITING

Gødstrup Hospital

Herning, , Denmark

Site Status RECRUITING

Horsens Hospital

Horsens, , Denmark

Site Status RECRUITING

Randers Hospital

Randers, , Denmark

Site Status RECRUITING

Silkeborg Hospital

Silkeborg, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Annette de Thurah, CNS, MPH, PHD

Role: CONTACT

+4529120722

Sofie B Vestergaard, RN, MSc, PhD-fellow

Role: CONTACT

+4523425312

Facility Contacts

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Annette de Thurah, CNS, MPH, PHD

Role: primary

+4529120722

Sofie B Vestergaard, RN, MSc, PhD-fellow

Role: backup

+4523425312

Sara Vildhøj, MD, PHD

Role: primary

Jakob B Andersen, MD, PHD

Role: primary

+4578426961

Stine G Skov, RN

Role: primary

Thomas Andersen, MD, PHD

Role: primary

Other Identifiers

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2096-00035B

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

1-10-72-165-24

Identifier Type: -

Identifier Source: org_study_id

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