Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds: A Randomized Clinical Trial
NCT ID: NCT06957964
Last Updated: 2025-05-06
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
70 participants
INTERVENTIONAL
2025-03-25
2025-06-25
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
NONE
Study Groups
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Participants with Negative Pressure Wound Therapy
In group A, Negative Pressure Wound Therapy will be applied at end of laparotomy. Participants will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics course. Patients will be followed-up in OPD for 30 days and will be assessed in terms of surgical site infection and re operation.
Negative Pressure Wound Therapy
Negative Pressure Wound Therapy is an intervention in which a suction is applied at applied thus creating a negative pressure which not only removes any exudate but also aids in formation of granulation tissue. NPWT is provided along with empirical prophylactic antibiotics
Standard Antibiotic Treatment
According to hospital antibiogram, empirical antibiotics are given prophylactically
Participants without Negative Pressure Wound Therapy
In group B, Negative Pressure Wound Therapy will be applied at end of laparotomy. Participants will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics course. Patients will be followed-up in OPD for 30 days and will be assessed in terms of surgical site infection and re operation.
Standard Antibiotic Treatment
According to hospital antibiogram, empirical antibiotics are given prophylactically
Interventions
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Negative Pressure Wound Therapy
Negative Pressure Wound Therapy is an intervention in which a suction is applied at applied thus creating a negative pressure which not only removes any exudate but also aids in formation of granulation tissue. NPWT is provided along with empirical prophylactic antibiotics
Standard Antibiotic Treatment
According to hospital antibiogram, empirical antibiotics are given prophylactically
Eligibility Criteria
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Inclusion Criteria
* Undergoing laparotomy under general anaesthesia
* ASA I-II
Exclusion Criteria
* Pregnant patients
* Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere
20 Years
70 Years
ALL
No
Sponsors
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Dr Hamail Khanum
OTHER
Responsible Party
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Dr Hamail Khanum
Head of Department Surgery
Principal Investigators
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Professor Dr Maratab Ali, MBBS FCPS
Role: STUDY_DIRECTOR
Gulab Devi Hospital
Locations
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Gulab Devi Hospital Lahore
Lahore, Punjab Province, Pakistan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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280
Identifier Type: -
Identifier Source: org_study_id
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