Virtual Reality During Skin Prick Test

NCT ID: NCT06952192

Last Updated: 2025-04-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

108 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-01

Study Completion Date

2025-02-01

Brief Summary

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Skin prick testing (SPT) is a cornerstone diagnostic procedure for identifying allergic sensitizations in pediatric patients. Despite being minimally invasive, it often provokes considerable anxiety, fear, and pain, potentially compromising test accuracy due to poor compliance. Virtual Reality (VR) has emerged as a promising non-pharmacological tool for procedural distress management, yet its application in allergy diagnostics remains underexplored.

To evaluate the effectiveness of VR in reducing procedural anxiety, fear, and pain, and in improving compliance in children undergoing SPT.

Detailed Description

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Conditions

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Allergy

Keywords

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virtual reality skin prick test pediatric allergy anxiety pain compliance

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Virtual reality

Group Type EXPERIMENTAL

Virtual reality

Intervention Type DEVICE

VR application via a head-mounted display one minute before and throughout the SPT procedure. The VR intervention utilized a Samsung Gear VR headset (Samsung, Seoul, South Korea) in conjunction with a Samsung S7 or S8 mobile device to provide an immersive and engaging experience. Children were allowed to choose from a range of age-appropriate VR content designed to enhance engagement and relaxation. Prior to the procedure, children were trained on how to use the headset by study staff to ensure a smooth experience.

Standard of care

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Virtual reality

VR application via a head-mounted display one minute before and throughout the SPT procedure. The VR intervention utilized a Samsung Gear VR headset (Samsung, Seoul, South Korea) in conjunction with a Samsung S7 or S8 mobile device to provide an immersive and engaging experience. Children were allowed to choose from a range of age-appropriate VR content designed to enhance engagement and relaxation. Prior to the procedure, children were trained on how to use the headset by study staff to ensure a smooth experience.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* a confirmed history of allergic symptoms related to either environmental or food allergens
* between 4 and 18 years of age

Exclusion Criteria

* history of seizure disorders,
* motion sickness,
* severe developmental delay,
* non-Italian-speaking patients
* Participants who had used systemic antihistamines or corticosteroids within the past seven days
Minimum Eligible Age

4 Years

Maximum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federico II University

OTHER

Sponsor Role lead

Responsible Party

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Roberto Berni Canani, MD, PhD

Full Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Univeristy of Naples Federico II

Naples, , Italy

Site Status

Countries

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Italy

Other Identifiers

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11n24

Identifier Type: -

Identifier Source: org_study_id