Study of CM512 in Patients With Moderate-to-Severe Atopic Dermatitis
NCT ID: NCT06947980
Last Updated: 2025-08-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE2
200 participants
INTERVENTIONAL
2025-06-19
2026-11-07
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Group 1
Placebo Comparator
Placebo subcutaneous injection
Group 2
CM512
CM512 subcutaneous injection
Group 3
CM512
CM512 subcutaneous injection
Group 4
CM512
CM512 subcutaneous injection
Group 5
Placebo Comparator
Placebo subcutaneous injection
Interventions
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Placebo Comparator
Placebo subcutaneous injection
CM512
CM512 subcutaneous injection
Eligibility Criteria
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Inclusion Criteria
* EASI≥16 at Screening and Baseline visits;
* Investigator's Global Assessment (IGA) score of≥3 at Screening and Baseline visits;
* 10% Body Surface Area (BSA) of AD involvement at Screening and Baseline visits;
* Mean of weekly Pruritus Numeric Rating Scale (NRS) severity score≥4 at Baseline;
Exclusion Criteria
* Concurrent disease/status which may potentially affect the efficacy/safety judgement.
* Organ dysfunction.
* Pregnancy.
* Other.
18 Years
75 Years
ALL
No
Sponsors
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Keymed Biosciences Co.Ltd
INDUSTRY
Responsible Party
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Principal Investigators
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Jianzhong Zhang
Role: PRINCIPAL_INVESTIGATOR
Peking University People's Hospital
Locations
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Peking University People's hospital
Beijing, , China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CM512-101102
Identifier Type: -
Identifier Source: org_study_id
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