Comparison of Anterior Chamber Depth in High Myopes

NCT ID: NCT06946043

Last Updated: 2025-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-09-30

Study Completion Date

2026-10-30

Brief Summary

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This study aims to compare the accuracy and reliability of anterior chamber depth (ACD) measurements obtained using three imaging modalities: anterior segment optical coherence tomography (A-S OCT), ultrasound biomicroscopy (UBM), and the Pentacam Scheimpflug imaging system. The research focuses on high myopic patients and evaluates the consistency and correlation of these measurements with the degree of myopia.

Detailed Description

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The research is a cross-sectional, prospective, observational cohort study conducted in ophthalmological settings at Assiut University Hospital, Elforsan Center, and Tyba Center. It investigates the anterior chamber depth (ACD) in high myopes using three advanced diagnostic imaging tools:

Anterior Segment Optical Coherence Tomography (A-S OCT): A non-invasive imaging technique for high-resolution cross-sectional imaging of the anterior segment.

Ultrasound Biomicroscopy (UBM): An imaging method that uses high-frequency ultrasound to visualize anterior segment structures.

Pentacam HR (Scheimpflug Imaging System): A device that provides three-dimensional imaging of the anterior chamber.

The primary objective is to determine the mean differences in ACD measurements among these devices. Secondary objectives include assessing the correlation between ACD measurements and the degree of myopia, as well as evaluating the repeatability of measurements for each device.

Conditions

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Anterior Chamber Depth

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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adult patients (aged 18 years or older) with high myopia

The study population consists of adult patients (aged 18 years or older) with high myopia, defined as an axial length greater than 26 mm or a refractive error exceeding -6.00 diopters (D). Participants must be able to fixate for imaging procedures.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 years or older

* High myopes with axial length \>26mm or , and refractive error \> -6 ,00 D
* Ability to fixate for OCT and Pentacam imaging

Exclusion Criteria

* History of ocular surgery or trauma

* Presence of corneal pathology
* Active ocular inflammation
* Inability to fixate for imaging procedure
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Manar Moner jawarji

resident at the ophthalmology department

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Smith A, Johnson B, Lee C. Anterior chamber depth measurement in high myopia: A comparative analysis. J Cataract Refract Surg. 2021;47(5):612-620.

Reference Type BACKGROUND

Wan T, Ding X, Sun Y. Swept-source OCT for anterior segment imaging in high myopia. BMC Ophthalmol. 2021;21(1):62.

Reference Type BACKGROUND

Other Identifiers

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anterior chamber depth measure

Identifier Type: -

Identifier Source: org_study_id

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