Potential of Gayo Arabica Coffee Skin

NCT ID: NCT06940076

Last Updated: 2025-04-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE2

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-01

Study Completion Date

2024-11-30

Brief Summary

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The purpose of this study was to assess the effectiveness of gayo arabica coffee skin extract cream in the prevention of skin aging

Detailed Description

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Conditions

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Skin Aging

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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skin aging patients

Group Type EXPERIMENTAL

gayo arabica coffee skin extract cream

Intervention Type DRUG

Assessment of glagou scale, skin analyzer, corneometer, and tewameter was done before and after the treatment . The subject will receive directions on how to use the cream before the study starts. The cream was used 2 times daily (7.40 AM and 1.00 PM) for 8 weeks.

Interventions

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gayo arabica coffee skin extract cream

Assessment of glagou scale, skin analyzer, corneometer, and tewameter was done before and after the treatment . The subject will receive directions on how to use the cream before the study starts. The cream was used 2 times daily (7.40 AM and 1.00 PM) for 8 weeks.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Women.
* have skin aging condition aged 30-60 years.
* Willing to participate in research based on research protocols.
* Before the research begins, research subjects are willing to sign informed consent and participate in the research until completion according to the research provisions from initial examination, re-control, and treatment until completion).

Exclusion Criteria

* History of allergy to one of the ingredients in the cream.
* have a skin disorder and are undergoing treatment for skin disease.
* Undergoing treatment and use of facial cream in the last 1 month.
* History of allergy to coffee.
Minimum Eligible Age

30 Years

Maximum Eligible Age

60 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Wahyu Lestari

OTHER

Sponsor Role lead

Responsible Party

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Wahyu Lestari

Assistant Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Wahyu Lestari, MD

Role: PRINCIPAL_INVESTIGATOR

Department of dermatology, venereology, and aesthetic dr. Zainoel Abidin General Hospital Banda Aceh, Nanggroe Aceh Darussalam, Indonesia

Locations

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dr. Zainoel Abidin General Hospital

Banda Aceh, Special Region of Aceh, Indonesia

Site Status

Countries

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Indonesia

References

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Esquivel P, Jiménez VM. Functional Properties of Coffee and Coffee By-products. Food Res Int. 2012;5(3):1-9. doi:10.1016/j.foodres.2011.05.028

Reference Type BACKGROUND

Murthy PS, Madhava Naidu M. Sustainable Management of Coffee Industry By-products and Value Addition - A review. Resour Conserv Recycl. Published online 2012:1-10. doi:10.1016/j.resconrec.2012.06.005

Reference Type BACKGROUND

Sholichah E, Apriani R, Desnilasari D, Karim MA. Produk Samping Kulit Kopi Arabika dan Robusta Sebagai Sumber Polifenol Untuk Antioksidan dan Antibakteri. Balai Besar Ind Has Perkeb. Published online 2019:57-66.

Reference Type BACKGROUND

Iriondo-DeHond A, Elizondo AS, Iriondo-DeHond M, Rios MB, Mufari R, Mendiola JA, Ibanez E, Castillo MDD. Assessment of Healthy and Harmful Maillard Reaction Products in a Novel Coffee Cascara Beverage: Melanoidins and Acrylamide. Foods. 2020 May 12;9(5):620. doi: 10.3390/foods9050620.

Reference Type BACKGROUND
PMID: 32408584 (View on PubMed)

Ameca GM, Cerrilla MEO, Córdoba PZ, Cruz AD, Hernández MS, Haro JH. Chemical Composition and Antioxidant Capacity of Coffee Pulp. Cienc e Agrotecnologia. 2018;4(3):307-313. doi:10.1590/1413-70542018423000818

Reference Type BACKGROUND

Klingel T, Kremer JI, Gottstein V, Rajcic de Rezende T, Schwarz S, Lachenmeier DW. A Review of Coffee By-Products Including Leaf, Flower, Cherry, Husk, Silver Skin, and Spent Grounds as Novel Foods within the European Union. Foods. 2020 May 21;9(5):665. doi: 10.3390/foods9050665.

Reference Type BACKGROUND
PMID: 32455549 (View on PubMed)

Tuong W, Walker L, Sivamani RK. Polyphenols as novel treatment options for dermatological diseases: A systematic review of clinical trials. J Dermatolog Treat. 2015;26(4):381-8. doi: 10.3109/09546634.2014.991675. Epub 2014 Dec 30.

Reference Type BACKGROUND
PMID: 25424055 (View on PubMed)

Islam MT, Tabrez S, Jabir NR, Ali M, Kamal MA, da Silva Araujo L, De Oliveira Santos JV, Da Mata AMOF, De Aguiar RPS, de Carvalho Melo Cavalcante AA. An Insight into the Therapeutic Potential of Major Coffee Components. Curr Drug Metab. 2018;19(6):544-556. doi: 10.2174/1389200219666180302154551.

Reference Type BACKGROUND
PMID: 29512445 (View on PubMed)

Petruk G, Del Giudice R, Rigano MM, Monti DM. Antioxidants from Plants Protect against Skin Photoaging. Oxid Med Cell Longev. 2018 Aug 2;2018:1454936. doi: 10.1155/2018/1454936. eCollection 2018.

Reference Type BACKGROUND
PMID: 30174780 (View on PubMed)

Bosch R, Philips N, Suarez-Perez JA, Juarranz A, Devmurari A, Chalensouk-Khaosaat J, Gonzalez S. Mechanisms of Photoaging and Cutaneous Photocarcinogenesis, and Photoprotective Strategies with Phytochemicals. Antioxidants (Basel). 2015 Mar 26;4(2):248-68. doi: 10.3390/antiox4020248.

Reference Type BACKGROUND
PMID: 26783703 (View on PubMed)

Other Identifiers

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094/ETIK-RSUDZA/2024

Identifier Type: -

Identifier Source: org_study_id

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