Functionality and Clinical Correlates in TMD

NCT ID: NCT06937502

Last Updated: 2025-06-05

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 62 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2025-06-10
• Study Completion Date: 2025-08-10

Brief Summary

Temporomandibular disorders (TMD) are among the most common causes of orofacial pain and refer to structural and functional impairments related to the masticatory muscles, surrounding soft tissues, and/or the temporomandibular joint (TMJ). They negatively affect individuals physically, psychologically, and socially. The structural and functional impairments observed in TMD typically manifest as pain, restricted jaw movement, joint sounds, and muscle tension. In addition to these core symptoms, secondary issues such as chewing difficulties may also occur. Pain in TMD can negatively impact many orofacial functions, especially chewing. Functional impairment in individuals with TMD may result from pain, restricted jaw mobility, muscle tension, alterations in muscle activation, mandibular asymmetry, and morphological changes in the joint. These findings highlight the importance of addressing factors associated with functional impairment in individuals with TMD.

Pain severity is strongly associated with functional limitations of the TMJ and neck disability. Particularly in cases of muscular-origin TMD, significant impairments in neck muscle function and joint mobility have been observed. This condition directly affects jaw function and leads to a decrease in quality of life. The impact of TMD on quality of life is directly related to pain severity and functional limitations. As pain severity increases, limitations in daily activities and reductions in overall quality of life also increase. Therefore, a multidisciplinary approach to TMD is essential for pain management, functional rehabilitation, and improving quality of life.

The aim of this study is to investigate the relationships between functionality and pain, range of motion, neck disability, and quality of life in individuals with TMD. Understanding these relationships will form a basis for the effective management of TMD and improving individuals' quality of life.

Conditions

Temporomandibular Disorders (TMD); Functional Limitation; Pain Severity; Neck Disability; Quality of Life

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Temporomandibular Disorders - Functionality Study Group

Mandibular functionality will be assessed using the Mandibular Function Impairment Questionnaire. Active temporomandibular joint (TMJ) range of motion (ROM) will be measured with a caliper. Pain will be evaluated using the Visual Analog Scale (VAS), neck disability using the Neck Disability Index (NDI), and quality of life using the World Health Organization Quality of Life Questionnaire (WHOQOL).

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

• Voluntary participation in the study
• Aged between 18 and 55 years
• Diagnosed with temporomandibular disorders (TMD) and exhibiting at least one of the three main symptoms (jaw pain, limited mouth opening, and/or temporomandibular joint sound)
• A Mini-Mental State Examination (MMSE) score of 24 or higher
• Pain score of 3 or above on the Visual Analog Scale (VAS)

Exclusion Criteria

• History of complex surgery, trauma, chemoradiotherapy, and/or tumors involving the head and neck region
• Ongoing use of analgesics, anti-inflammatory or psychiatric medications, and/or substance abuse
• Significant tooth loss that interferes with chewing function
• Use of dental prosthesis
• Ongoing tooth pain
• Receiving any TMD-specific treatment prior to or during the evaluation period
• History of orthodontic treatment
• Diagnosis of disc displacement without reduction

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 55 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Istinye University

OTHER

Sponsor Role: lead

Responsible Party

Elif Kabasakal

LECTURER

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Istınye University, Istanbul,

Istanbul, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Central Contacts

Elif Kabasakal, MSc

Role: CONTACT

elif.kabasakal@istinye.edu.tr

05347093738

Facility Contacts

Elif Kabasakal

Role: primary

elif.kabasakal@istinye.edu.tr

05347093738

Other Identifiers

ISU-2025-003

Identifier Type: -

Identifier Source: org_study_id