Compassion-Based Intervention for Lung Cancer Caregivers (CBI-LCC)

NCT ID: NCT06930313

Last Updated: 2025-04-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-03-01

Study Completion Date

2028-02-28

Brief Summary

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Objectives: This 3-year study aims to develop, refine, and evaluate a brief compassion-based intervention specifically designed for family caregivers of lung cancer patients. In the first year, the primary focus will be on developing the intervention content and assessing its feasibility and acceptability. In the second and third years, the goal will be to assess the intervention's effects on depression and anxiety.

Method: In the first year, the intervention will be developed in three stages. Initially, the intervention will be created based on compassion-focused theory and evidence-based exercises, incorporating feedback from family caregivers in previous studies and insights from professionals to ensure its relevance to lung cancer caregivers. Next, a pilot study will test the intervention's feasibility and acceptability with 30 family caregivers, using mixed methods to gather session-by-session feedback and assess recruitment, retention, and adherence. Following the pilot, the intervention will be revised based on participant and researcher feedback, preparing it for further study. In the second and third years, a randomized controlled trial (RCT) will be conducted with 84 participants randomly assigned to either the 4-session Brief Compassion-Based Intervention (BCI) or a single-session Telephone-Based Support and Education (TSE) control group. Outcomes, including depression, anxiety, caregiver stress, mindfulness, self-compassion, and self-efficacy, will be measured at baseline, immediately post-intervention, and at 3- and 6-month follow-ups. For data analysis, long-term follow-up quantitative data will be analyzed using the Generalized Estimating Equation (GEE) to examine group differences. Moderation and mediation analyses will be conducted to explore potential moderators and mechanisms of the intervention. Qualitative data from interviews will be analyzed using content analysis.

Expected Results: This study is expected to provide a comprehensive understanding of the feasibility, acceptability, and effectiveness of compassion-based interventions for lung cancer caregivers, contributing to their application in clinical care practice.

Detailed Description

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Conditions

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Compassion

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Arm 1: Experimental Arm Name: Brief Compassion-Based Intervention (BCI) Description: Participants in this arm will receive a 4-session Brief Compassion-Based Intervention (BCI) focused on managing depression and anxiety in family caregivers of lung cancer patients.

Arm 2: Control Arm Name: Telephone-Based Support and Education (TSE) Description: Participants in this arm will receive a single-session Telephone-Based Support and Education (TSE), providing general caregiving advice and emotional support.
Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

DOUBLE

Participants Investigators
Participant Masking Description: Participants will not be informed of their group allocation (Intervention or Control group). While participants will know the specific type of support they are receiving (e.g., Compassion-Based Intervention or Telephone-Based Support), they will not be aware of which group is considered the experimental intervention.

Investigator Masking: Investigators responsible for data collection and analysis will be blinded to group allocation to maintain objectivity.

Study Groups

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Brief Compassion-Based Intervention (BCI)

Participants in this arm will receive a 4-session Brief Compassion-Based Intervention (BCI) focused on managing depression and anxiety in family caregivers of lung cancer patients.

Group Type EXPERIMENTAL

Brief Compassion-Based Intervention (BCI)

Intervention Type BEHAVIORAL

The intervention program is based on Compassion-Focused Therapy (CFT) and incorporates evidence-based compassion exercises.Drawing on insights from the literature, the program includes:Session 1: Introduction to caregiving challenges and emotional systems. Includes a soothing breathing exercise and group discussion on caregiving stress.

Session 2: Cultivating self-compassion. Includes reflecting on emotions, guided meditation, and a compassionate body scan practice.

Session 3: Transforming self-criticism into self-compassion. Caregivers explore self-critical thoughts, practice reframing, and engage in compassionate dialogue.

Session 4: Building resilience and connections. Focuses on gratitude, setting boundaries, and loving-kindness meditation, ending with daily intention setting.

Telephone-Based Support and Education (TSE)

Participants in this arm will receive a single-session Telephone-Based Support and Education (TSE), providing general caregiving advice and emotional support.

Group Type ACTIVE_COMPARATOR

Telephone-Based Support and Education (TSE)

Intervention Type BEHAVIORAL

The session will address their questions and concerns, provide psychological support for managing difficult emotions (e.g., anxiety, fear, sadness, and guilt), and emphasize the importance of self-care, encouraging them to take time for themselves and seek support when needed.

Interventions

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Brief Compassion-Based Intervention (BCI)

The intervention program is based on Compassion-Focused Therapy (CFT) and incorporates evidence-based compassion exercises.Drawing on insights from the literature, the program includes:Session 1: Introduction to caregiving challenges and emotional systems. Includes a soothing breathing exercise and group discussion on caregiving stress.

Session 2: Cultivating self-compassion. Includes reflecting on emotions, guided meditation, and a compassionate body scan practice.

Session 3: Transforming self-criticism into self-compassion. Caregivers explore self-critical thoughts, practice reframing, and engage in compassionate dialogue.

Session 4: Building resilience and connections. Focuses on gratitude, setting boundaries, and loving-kindness meditation, ending with daily intention setting.

Intervention Type BEHAVIORAL

Telephone-Based Support and Education (TSE)

The session will address their questions and concerns, provide psychological support for managing difficult emotions (e.g., anxiety, fear, sadness, and guilt), and emphasize the importance of self-care, encouraging them to take time for themselves and seek support when needed.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Primary family caregiver of a person with newly diagnosed lung cancer (within one year of diagnosis)
* Aged 20 years or older
* Access to a computer or smartphone with internet connection at home

Exclusion Criteria

* Currently receiving psychological therapy
* Diagnosed with a severe mental illness and taking medication for it (e.g.,psychosis, bipolar disorder)
* Previous experience with mindfulness or self-compassion training
Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Science and Technology Council

FED

Sponsor Role collaborator

Taipei Medical University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Taipei Medical University

Taipei, Taiwan, Taiwan

Site Status

Countries

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Taiwan

Central Contacts

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Chia-Chen Hsieh, PhD

Role: CONTACT

+886 2 2736 1661 ext. 6306

Facility Contacts

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Taipei Medical University

Role: primary

+886-2-2736-1661

Other Identifiers

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IRB Approval Number

Identifier Type: OTHER

Identifier Source: secondary_id

N202411055

Identifier Type: -

Identifier Source: org_study_id

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