Hand Jing-Well Points Stimulation to Treat Disorders of Consciousness

NCT ID: NCT06927713

Last Updated: 2025-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-12

Study Completion Date

2026-11-30

Brief Summary

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The purpose of this academic lead study is to explore the ideal stimulation strategies at Hand twelve jing-well points in patients with disorders of consciousness.

Detailed Description

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Conditions

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Disorders of Consciousness Due to Severe Brain Injury

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Bloodletting Puncture

Bloodletting puncture at hand twelve jing-well points for 5 consecutive days, once a day, combined with conventional medical treatment.

Group Type EXPERIMENTAL

Bloodletting Acupuncture

Intervention Type OTHER

Bloodletting was applied to the right hand first and then the left hand in the order of Shaoshang (LU 11), Shangyang (LI 1), Zhongchong (PC 9), Guanchong (TE 1), Shaochong (HT 9) and Shaoze (SI 1).

Transcutaneous electrical stimulation

Transcutaneous electrical acupoint stimulation at hand twelve jing-well points for 5 consecutive days, once a day, combined with conventional medical treatment.

Group Type EXPERIMENTAL

Transcutaneous electrical stimulation

Intervention Type DEVICE

Transcutaneous electrical acupoint stimulation at hand twelve jing-well points.

Control

Control group was treated with conventional medical treatment.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Bloodletting Acupuncture

Bloodletting was applied to the right hand first and then the left hand in the order of Shaoshang (LU 11), Shangyang (LI 1), Zhongchong (PC 9), Guanchong (TE 1), Shaochong (HT 9) and Shaoze (SI 1).

Intervention Type OTHER

Transcutaneous electrical stimulation

Transcutaneous electrical acupoint stimulation at hand twelve jing-well points.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age: 18-80 years old
* From 7 to 90 days since brain injury
* Diagnosed in VS/UWS or MCS as defined by at least two CRS-R assessments performed during the screening period
* Acquired cerebral damage of known etiology
* Intact hand skin
* Informed consent given by the legal surrogate

Exclusion Criteria

* Patients who continuously receive sedative drugs and Na+ or Ca2+ channel blockers (e.g., carbamazepine) or NMDA receptor antagonists (e.g., dextromethorphan)
* History of previous serious、progressive neurological disorder prior to the brian injury
* Epilepsy and seizure
* Unstable vital signs or life-threatening comorbidities
* Active implant (e.g., cardiac pacemakers/defibrillators, deep brain stimulators, ventriculoperitoneal shunt, etc)
* Documented pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Xijing Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Xijing Hospital

Xi'an, Shaanxi, China

Site Status RECRUITING

Countries

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China

Facility Contacts

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chairman of committee

Role: primary

86-029-84771794

Other Identifiers

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KY20252094JIANGWEN

Identifier Type: -

Identifier Source: org_study_id

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