Antecolic Versus Retrocolic Gastrojejunostomy During Whipple's Procedure

NCT ID: NCT06914349

Last Updated: 2025-06-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

76 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-30

Study Completion Date

2029-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Aim: This randomized clinical study aims to compare occurrence of DGE in patients undergoing either antecolic or retrocolic gastrojejunostomy following pancreaticoduodenectomy.

Methods: Participants of this study will be patients undergoing pylorus preserving pancreaticoduodenectomy at the Surgical Department of the University Hospital of Larissa. Patients will be randomized to undergo either an antecolic or a retrocolic gastrojejunostomy and the occurrence of DGE will then be compared between the two groups. Individuals younger than 18 or older than 75 years old, as well as patients who do not consent to participate in this trial, will be excluded.

Expected results: Based on available literature, antecolic gastrojejunostomy may be related with a lower incidence of DGE, without a statistically significant difference between the two methods. We aim to show if one of the two methods of gastrointestinal reconstruction (antecolic versus retrocolic) affects DGE.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pancreatic Cancer Resectable Pancreas Neoplasms

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Antecolic gastrojejunostomy

Group Type ACTIVE_COMPARATOR

Antecolic gastrojejunostomy

Intervention Type PROCEDURE

Gastrojejunostomy in front of the transverse colon

Retrocolic gastrojejunostomy

Group Type ACTIVE_COMPARATOR

Retrocolic gastrojejunostomy

Intervention Type PROCEDURE

Gastrojejunostomy through the transverse mesocolon

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Antecolic gastrojejunostomy

Gastrojejunostomy in front of the transverse colon

Intervention Type PROCEDURE

Retrocolic gastrojejunostomy

Gastrojejunostomy through the transverse mesocolon

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age over 18 years old
* Elective pancreaticoduodenectomy
* Signed consent form

Exclusion Criteria

* Age under 18 years old
* Patients who are participants in other trials that may affect the results of this study
* Patients who do not consent to participate in the study
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

University of Thessaly

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Chrysoula-Christina Kolla

MD, Msc

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Dimitrios Symeonidis

Role: STUDY_CHAIR

University of Thessaly

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

University of Thessaly

Larissa, , Greece

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Greece

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Chrysoula C Kolla

Role: CONTACT

+306983075706

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Chrysoula-Christina Kolla

Role: primary

6983075706

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

University hospital of Larissa

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.