Analyzing the Effect of Disinfection Additives on the Linear Dimensional Stability of Dental Alginate Impressions: A Quasi-Experimental Comparative Study

NCT ID: NCT06899672

Last Updated: 2025-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-04-01

Study Completion Date

2025-10-01

Brief Summary

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This quasi-experimental comparative study investigates the effects of incorporating various self-disinfecting agents-0.2% Chlorhexidine (CHX), 1% Chitosan solution, 0.2% Silver Nitrate (AgNO3), green-synthesized Silver Nanoparticles (AgNPs), and 15% PVP-Iodine-on the linear dimensional stability of dental alginate impressions. Alginate is widely used in dentistry but is prone to dimensional changes and contamination. This study aims to assess whether integrating these disinfectants can reduce microbial risks without compromising the material's dimensional accuracy, thereby improving infection control and the precision of dental prostheses

Detailed Description

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Conditions

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Dimensional Changes

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Control Group (Distilled Water)

Participants (specimens) will receive alginate mixed with distilled water without any disinfectant, serving as the baseline group

Group Type EXPERIMENTAL

Alginate mixed with distilled water

Intervention Type OTHER

Alginate will be mixed with distilled water only, without any disinfectant additive, to serve as the control for comparison

CHX Group (0.2% Chlorhexidine)

Participants (specimens) will receive alginate mixed with 0.2% Chlorhexidine solution to assess its effect on dimensional stability

Group Type EXPERIMENTAL

0.2% Chlorhexidine + Alginate

Intervention Type OTHER

Alginate will be mixed with 0.2% Chlorhexidine solution to evaluate its effect on the linear dimensional stability of alginate impressions

Chitosan Group (1% Chitosan)

Participants (specimens) will receive alginate mixed with 1% Chitosan solution to evaluate its effect on dimensional stability

Group Type EXPERIMENTAL

1% Chitosan + Alginate

Intervention Type OTHER

Alginate will be mixed with 1% Chitosan solution to assess its influence on the linear dimensional stability of alginate impressions

Silver Nitrate Group (0.2% Silver Nitrate)

Participants (specimens) will receive alginate mixed with 0.2% Silver Nitrate solution to evaluate its effect on dimensional stability

Group Type EXPERIMENTAL

0.2% Silver Nitrate + Alginate

Intervention Type OTHER

Alginate will be mixed with 0.2% Silver Nitrate solution to determine its effect on the dimensional stability of alginate impressions

Silver Nanoparticles Group (Green-Synthesized AgNPs)

Participants (specimens) will receive alginate mixed with green-synthesized silver nanoparticles to investigate its impact on dimensional stability

Group Type EXPERIMENTAL

Green-synthesized Silver Nanoparticles + Alginate

Intervention Type OTHER

Alginate will be mixed with a solution of green-synthesized Silver Nanoparticles to investigate its effect on the dimensional stability of alginate impressions

PVP-Iodine Group (15% Povidone-Iodine)

Participants (specimens) will receive alginate mixed with 15% Povidone-Iodine solution to determine its effect on dimensional stability

Group Type EXPERIMENTAL

15% Povidone-Iodine + Alginate

Intervention Type OTHER

Alginate will be mixed with 15% Povidone-Iodine solution to analyze its influence on the dimensional stability of alginate impressions

Interventions

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Alginate mixed with distilled water

Alginate will be mixed with distilled water only, without any disinfectant additive, to serve as the control for comparison

Intervention Type OTHER

0.2% Chlorhexidine + Alginate

Alginate will be mixed with 0.2% Chlorhexidine solution to evaluate its effect on the linear dimensional stability of alginate impressions

Intervention Type OTHER

1% Chitosan + Alginate

Alginate will be mixed with 1% Chitosan solution to assess its influence on the linear dimensional stability of alginate impressions

Intervention Type OTHER

0.2% Silver Nitrate + Alginate

Alginate will be mixed with 0.2% Silver Nitrate solution to determine its effect on the dimensional stability of alginate impressions

Intervention Type OTHER

Green-synthesized Silver Nanoparticles + Alginate

Alginate will be mixed with a solution of green-synthesized Silver Nanoparticles to investigate its effect on the dimensional stability of alginate impressions

Intervention Type OTHER

15% Povidone-Iodine + Alginate

Alginate will be mixed with 15% Povidone-Iodine solution to analyze its influence on the dimensional stability of alginate impressions

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Dental stone casts free from excessive porosity, fractures, or other visible defects that could affect dimensional stability measurements.
* Typodont models with intact maxillary arch configurations.

Exclusion Criteria

* Distorted impressions, under-extended impressions, impressions that detach from the tray before pouring, and impressions with voids, on visual inspection.
* Dental cast with a fracture component, incomplete pouring, and those with voids or bubbles.
Minimum Eligible Age

60 Minutes

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Altamash Institute of Dental Medicine

OTHER

Sponsor Role lead

Responsible Party

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Dr. Aiman yaseen

Bachelor of Dental Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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AIDM/ERC/10/2024/01

Identifier Type: -

Identifier Source: org_study_id

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