Dose Response of Exercise for Arthritis Management

NCT ID: NCT06880653

Last Updated: 2025-05-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

285 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-03-28

Study Completion Date

2029-04-30

Brief Summary

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The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.

Detailed Description

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All participants will be randomly assigned a physical activity goal (45 min/week, 90 min/week, or 150 min/week). To help participants achieve goals, they will receive a 6 month program which includes the Arthritis Foundation's Walk With Ease Guidebook, behavioral lessons, a Fitbit, and monthly coaching calls. Participants may also receive additional calls, texts, or emails if they are struggling to meet their physical activity goals.

Conditions

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Arthritis Rheumatoid Arthritis (RA) Gout Fibromyalgia (FM) Osteoarthritis Lupus Erythematosus, Systemic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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45 minutes/week

Participants will be given a goal of 45 minutes/week of moderate-to-vigorous intensity physical activity

Group Type EXPERIMENTAL

DREAM Adaptive Intervention

Intervention Type BEHAVIORAL

6-month physical activity program (Dose Response of Exercise for Arthritis Management (DREAM)) which includes monthly phone coaching, Walk With Ease Guidebook, behavioral lessons, and a Fitbit. Participants may receive additional contact (email, text, or phone) if they struggle to meet activity goal.

90 minutes/week

Participants will be given a goal of 90 minutes/week of moderate-to-vigorous intensity physical activity

Group Type EXPERIMENTAL

DREAM Adaptive Intervention

Intervention Type BEHAVIORAL

6-month physical activity program (Dose Response of Exercise for Arthritis Management (DREAM)) which includes monthly phone coaching, Walk With Ease Guidebook, behavioral lessons, and a Fitbit. Participants may receive additional contact (email, text, or phone) if they struggle to meet activity goal.

150 minutes/week

Participants will be given a goal of 150 minutes/week of moderate-to-vigorous intensity physical activity

Group Type EXPERIMENTAL

DREAM Adaptive Intervention

Intervention Type BEHAVIORAL

6-month physical activity program (Dose Response of Exercise for Arthritis Management (DREAM)) which includes monthly phone coaching, Walk With Ease Guidebook, behavioral lessons, and a Fitbit. Participants may receive additional contact (email, text, or phone) if they struggle to meet activity goal.

Interventions

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DREAM Adaptive Intervention

6-month physical activity program (Dose Response of Exercise for Arthritis Management (DREAM)) which includes monthly phone coaching, Walk With Ease Guidebook, behavioral lessons, and a Fitbit. Participants may receive additional contact (email, text, or phone) if they struggle to meet activity goal.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* 18 years or older
* Have a doctor diagnosed form of arthritis, rheumatoid arthritis, gout, lupus, or fibromyalgia
* Ability to read and write in English

Exclusion Criteria

* Have any contraindications to exercise (besides arthritis)
* Engage in ≥30 min/week of Actigraph assessed MVPA
* Are pregnant, breastfeeding, or planning to become pregnant in the next year
* Are planning to relocate out of the Columbia, SC area in the next 12 months,
* Do not have a device compatible with Fitbit
* Have uncontrolled hypertension (e.g., systolic blood pressure \> 160 mmHg or diastolic blood pressure \> 100 mmHg)
* Plan to have a surgery that affects mobility in the next 12 months
* Have a serious cognitive impairment.
* Not willing to be randomized to any of the 3 conditions, do not believe they could adhere to the goals, or do not believe they could achieve the highest dose of activity (150 minutes/week).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centers for Disease Control and Prevention

FED

Sponsor Role collaborator

University of South Carolina

OTHER

Sponsor Role lead

Responsible Party

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Christine A Pellegrini, PhD

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christine Pellegrini, PhD

Role: PRINCIPAL_INVESTIGATOR

University of South Carolina

Locations

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University of South Carolina

Columbia, South Carolina, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Ellen Wingard

Role: CONTACT

803-777-1889

Facility Contacts

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Christine Pellegrini

Role: primary

803-777-0911

Other Identifiers

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U48DP006850

Identifier Type: NIH

Identifier Source: secondary_id

View Link

Pro00140006

Identifier Type: -

Identifier Source: org_study_id

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