Thoraco-laparoscopic Partial Esophagogastrectomy for Management of Esophageal Cancer

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-01

Study Completion Date

2027-09-01

Brief Summary

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Thoraco-laparoscopic partial esophagogastrectomy has emerged as a promising minimally invasive alternative, combining thoracoscopy and laparoscopy to reduce the trauma associated with open surgery.Early and intermediate-term outcomes provide critical information on both the oncological efficacy and functional benefits of the procedure. By examining recurrence rates within the first 12-24 months, this study will provide valuable insights into the oncological robustness of this approach compared to more invasive approaches.

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Detailed Description

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Conditions

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Esophageal Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Thoraco-laparoscopic partial esophagogastrectomy

Patients diagnosed with resectable esophageal cancer will undergo thoraco-laparoscopic partial esophagogastrectomy

Group Type EXPERIMENTAL

Thoraco-laparoscopic partial esophagogastrectomy

Intervention Type PROCEDURE

1. Laparoscopic Phase:

* The stomach is mobilized, and a part of it is resected to include the lower esophageal segment.
* Left gastric nodes, the splenic and common hepatic nodes are dissected.
* A gastric tube is created using endoscopic staplers for esophageal reconstruction and fixed to the proximal gastrectomy specimen using sutures
2. Thoracoscopic Phase:

* The patient is positioned in prone position
* Three small incisions are made in the thorax
* Further esophageal mobilization through a right thoracoscopy is performed in left lateral decubitus. Periesophageal nodes are retrieved en bloc. Left and right paratracheal and subcarinal lymph nodes are resected separately. The esophagus is transected at the tumor's proximal margin.
3. Reconstruction:

* An anastomosis (esophagogastric connection) is performed to restore continuity, typically using a circular stapler or hand-sewn technique.

Interventions

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Thoraco-laparoscopic partial esophagogastrectomy

1. Laparoscopic Phase:

* The stomach is mobilized, and a part of it is resected to include the lower esophageal segment.
* Left gastric nodes, the splenic and common hepatic nodes are dissected.
* A gastric tube is created using endoscopic staplers for esophageal reconstruction and fixed to the proximal gastrectomy specimen using sutures
2. Thoracoscopic Phase:

* The patient is positioned in prone position
* Three small incisions are made in the thorax
* Further esophageal mobilization through a right thoracoscopy is performed in left lateral decubitus. Periesophageal nodes are retrieved en bloc. Left and right paratracheal and subcarinal lymph nodes are resected separately. The esophagus is transected at the tumor's proximal margin.
3. Reconstruction:

* An anastomosis (esophagogastric connection) is performed to restore continuity, typically using a circular stapler or hand-sewn technique.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients diagnosed with resectable esophageal cancer (stages I-III).
* Suitable for thoraco-laparoscopic partial esophagogastrectomy.
* Eastern Cooperative Oncology Group (ECOG) performance status 0-2.

Exclusion Criteria

* Presence of distant metastasis at diagnosis.
* History of previous esophageal or gastric surgery.
* Contraindications to laparoscopy or thoracoscopy.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No